The article deals with results of combined physical therapy influences in workers with decreased functional resources. Findings are that newly designed physical therapy complex results in increased physical performance and functional resources of heart in examinees, as well as heals vegetative dysfunction and psychoemotional disturbances.

Chronic obstructive lung disease (COLD) is a chronic progressive disease requiring timely treatment. Short-acting ß2-agonists and M-cholinergic drugs are emergency medicines. Long-acting ß2-agonists and M-cholinergic drugs are basic preparations and occupy central place in therapy of patients varying in symptoms severity. Their combinations considerably improve pulmonary function parameters, life quality and reliably decrease dyspnea, if compared to monotherapy. Combination of indakaterol/glycopirronium is widely proved scientifically to influence COLD exacerbations, if compared to monotherapy with long-acting ß2-agonists and M-cholinergic drugs and with combined inhaled corticosteroids with long-acting ß2-agonists. Corticosteroidal therapy has secondary importance in COLD therapy after optimal bronchial dilation. Corticosteroids should be prescribed strictly on indications in cases where they are really effective.

Remaining negative tendencies in children health state, difficulties in pharmacologic correction of chronic diseases determine increasing interest of doctors to various natural and preformed physical factors in complex programs of prevention, treatment and rehabilitation. For scientific basis of dry carbonate baths in pediatrics, the authors conducted special studies in 84 children with bronchial asthma, in 100 children having frequent acute respiratory diseases. Results of the studies demonstrated expedient use of dry carbonate baths for bronchial asthma in children. Dry carbonate baths had favorable influence on clinical symptoms, allergic inflammation parameters. Findings are better bronchial permeability, decreased aeriness of pulmonary tissue and increased diaphragm mobility in children with bronchial asthma. Complex evaluation of dry carbonate baths efficiency in frequently ill children helped to reveal peculiarities of balneotherapy influence on clinical course of acute respiratory disease, functional state of vegetative nervous system, mucosal immunity. Lower frequency of acute respiratory diseases and less days absent in preschool institutions were seen.

The article presents contemporary possibilities of using halotherapy in prevention of acute respiratory diseases and treatment of frequently ill children. Frequent acute respiratory infections disorder functional activity of compensation mechanisms in child, decrease immunologic reactivity, alter local resistance in throat lining - that promotes persisting opportunistic pathogenic and pathogenic bacteria, chronic infection seat formation. Halotherapy is an effective sanitation method for children in schools. Dry highly dispersed aerosol of sodium chloride causes anti-inflammatory effect, decreases colonization activity of opportunistic pathogenic and pathogenic bacteria, stimulates protective potential of respiratory tract, lowers frequency of acute respiratory diseases in children.

The article deals with clinical features of pathologic scars, and criteria justifying their differentiation during stages of formation and stabilization of scarring process. Results of comparative analysis of main clinical parameters characterizing appearance and characteristics of scars are schematically generalized in specified unified study chart and diagrams. The authors described general principles of early differentiation and specified criteria to evaluate efficiency of pathologic scars correction.

Various types of hyperpigmentation are widely spread cause of visit to dermatologist and cosmetologist. Mostly a cosmetic defect, hyperpigmentation could decrease a life quality in patients. The article covers main contemporary methods to correct non-tumorous melanine skin hyperpigmentations, effective combinations of some therapeutic modalities. Observation included 32 patients with various clinical forms of nontumorous melanine skin hyperpigmentations, aged 27 to 68 years. The lesion was localized on face, decollete area and back of hands in 26 (81.2%) patients, in 6 (18.7%) patients - on trunk or extremities. The patients underwent local therapy with medications including glycolic acid, ascorbic acid and liquorice extract as a monotherapy, and combined with laser therapy (755 nm). Local therapy with medications including glycolic acid, ascorbic acid and liquorice extract as a monotherapy, and combined with laser therapy (755 nm) demonstrated high efficiency and could be considered as a safe method of esthetic correction of hyperpigmentation, but combined therapy appeared considerably more therapeutically effective.

The review covers literature data on treatment of psoriasis patients with concurrent metabolic syndrome by genetic engineering preparations of biologic therapy. Special attention is paid to indications for genetic engineering preparations of biologic therapy, differential selection of such preparations for patients to decrease risks of the disease deterioration.

Nonsteroid anti-inflammatory medicines are most widely used medicaments with pain-killing, anti-inflammatory and antipyretic action. Systematic intake of nonsteroid anti-inflammatory medicines frequently affect whole length of gastrointestinal tract, with erosions and ulcers formation, complicated by gastro-intestinal bleeding. Given systemic pain-killing action of nonsteroid anti-inflammatory medicines, these complications often are asymptomatic, being an accidental finding at endoscopic examination. Selective inhibitors intake does not rule out risk of gastric and intestinal problems due to nonsteroid anti-inflammatory medicines, thus prevention of those complications remain a topical problems nowadays. Special attention is paid to possible protection of gastric and intestinal lining. The authors listed major risk factors and complication types induced by nonsteroid anti-inflammatory medicines, considered main groups of medications used in treatment of those gastrointestinal disorders. Special accent is made on advantages of relatively new cytoprotector drug Rebamipid - at present single inductor of endogenous prostaglandine synthesis. Clinical data supporting its high efficiency and low incidence of adverse effects are presented.

The article contains analysis of parameters characterizing health state in able-bodied population in Russia. The authors analyzed standardized mortality parameters in able-bodied population of Russian Federation, of EU countries, and studied relationships between work conditions and mortality from leading causes among able-bodied males in RF regions.

The article covers hygienic aspects of health formation in adolescent and young adult students of primary and secondary professional schools, connected with trend to worsening adolescents' health state, decreased sanitary well-being of educational institutions, characters of occupational and educational load, prevalence of negative behavioural patterns associated with health risks. The authors revealed risks of social and occupational dysadaptation with malformed occupational self-determination. The article stresses necessity to create contemporary system of occupational orientation, including medical professional counselling and orientation, demonstrates necessity to increase control over safety in adolescents' education at industrial workplaces within a concept of professional education development with practice-oriented training of qualified personnel.

Early diagnosis of main non-infectious diseases leading to disablement and mortality among able-bodied population is a main goal of prophylactic medical examinations. The authors stress importance of the examination quality, absence of formal approach, with participation of experienced specialists. Results of the examination are objective grounds for further examination by local specialists.

The article covers qualitative and quantitative analysis of certain parameters concerning efficiency of preliminary and periodic medical examinations for high mountain mining enterprise. In comparison with local governmental institutions, specially founded private medical clinic provides higher quality of medical examinations in certain parameters, as well as in characters of subsequent stuffers' appeals for medical aid at mine.