The study was aimed to compare efficiency of optimized and combined treatment and rehabilitation in post-apoplexy patients, using standard therapy, cytoflavin and COBS-training. The study involved 51 patients in early (n = 25) and late (n = 26) recovery periods after CVA. Reference groups included patients in early (n = 15) and late (n = 15) recovery periods, receiving basic therapy. Evaluations included the patients' complaints change, activity index (Bartel scale), neurologic state (NIHSS scale), static and locomotory disorders intensity (M.E. Tinetti scale), ultrasound dopplerography, MALDI-TOF-TOF mass spectrometry of serum. Implementation of cytoflavin and COBS-training in CVA patients in early recovery period resulted in better life quality, decrease in neurologi deficit, less static and locomotory disorders, increased average blood velocity, RI, PI on ICA siphon and lower average blood velocity, RI, PI on MCA in comparison with reference groups and CVA patients in late recovery period. Findings are molecular groups of cellular apoptosis, autophagy, necroptosis, ER stress in serum - explanation of additional links of cytoflavin and COBS-training action mechanism in post-apoplexy patients.

Trophic ulcers are complications of chronic venous insufficiency in 15-18% of cases and appear in 1-2% of ablebodied population. The frequency increases with age up to 4-5% among the patients aged over 65, and radical removal of the disease can be achieved only in one tenth of the patients. With that, even healed trophic ulcers recur frequently: after surgery in 4,8-31,6% of cases (according to various authors), after conservative treatment in 15-100% of cases. Main treatment modalities for trophic ulcers are medical and surgical. Recent researches necessitate including physical therapy methods into the treatment complex, as combined techniques that enable to improve results of various treatment variants.

Complex analysis of changes in clinical, laboratory and ultrasound manifestations in rheumatoid arthritis revealed relationships between the pathologic process activity, the disease duration, its X-ray stage and ultrasound signs. Manifestation of rheumatoid arthritis is characterized by predominant proliferation and exudation in soft tissues inside joints, tendopathies, chondral plate alterations as hyaline destruction. Articular cartilage erosions can be seen even in 2.8 months after destructive arthritis manifestation. Diagnostic criteria of early rheumatoid arthritis are: articular disorders location, articular syndrome variant (mono-, oligo- and polyarthritic; seropositiveness on rheumatoid factor and ACCP), chondral plate state according to ultrasound examination.

The study was aimed to evaluate treatment efficiency of patients with chronic cardiac failure via therapeutic teaching. The study included 137 patients. Implementation of therapeutic teaching into treatment of chronic cardiac failure patients resulted in less number of patients with III functional grade, better tolerance to physical exertion, more awareness, greater number of patients with self-control skills and adherence to recommended treatment, better life quality of the patients. Medical and social significance manifested in less frequent hospitalizations and calls for emergency medical care.

Oncologic morbidity has a tendency to steady rise. Treatment of oncologic patients, aimed to remove or cease malignant cells growth and prevent metastases, has considerable side effects and is conducted on psychologic stress background. Rehabilitation measures hence get crucial importance. Rehabilitation of oncologic patients in complex treatment is a multi-stage continuous recovery process that includes various influences. Correct implementation of physical therapy factors in rehabilitation program causes no tumor growth and metastases, and sometimes inhibits tumor cells growth. On recommendations of sanatorium-and-spa treatment for oncologic patients, the complex promotes rapid recovery of disordered functions, activation of adaptive responses, psychologic and social adjustment.

The study covered functional peculiarities in 541 professional sportsmen. Mitral valve prolapse (in 132 examinees) appeared to be associated with reliably lower levels of reticulocytes, leucocytes, lymphocytes CD4+, immunoglobulines G, magnesium, and higher cortisol level, in comparison with the sportsmen having no mitral valve prolapse. The athletes with mitral valve prolapse demonstrated more frequent changes in ECG, reliably lower performance in treadmill test, slower recovery of heart rate after exertion is over.

The article covers main aspects of sanatorium-and-spa treatment in chronic skin diseases.

The study was aimed at features and efficiency of controlled halotherapy method in patients with occupational chronic obstructive lung disease (COLD). Examination covered 73 patients with occupational mild and moderate stages of COLD, aged 45 to 64. All the patients were randomized to 2 comparable groups - main and reference (37 and 36 examinees respectively). The main group in addition to conventional medical therapy received courses of controlled halotherapy (10 procedures with certain concentration of sodium chloride dry aerosol in accordance to methodic recommendations). Based on complex evaluation of clinical, functional and laboratory methods, the authors assessed efficiency of controlled halotherapy in patients with occupational COLD. Considerable improvement was seen: for mild COLD - in 40% of cases, for moderate COLD - in 30%, with general efficiency for these patients of 90 and 85% respectively. Analysis of the results obtained enables to evaluate controlled halotherapy as an effective method of rehabilitation and prevention in occupational COLD patients.

Based on studies of certain gene-candidate polymorphism, the authors studied markers of early development and unfavorable course of pneumoconiosis in post-contact period. Analysis covered occurrence of genotypes and allels of I/D polymorphism of gene CCR5, 4a/b polymorphism of gene NOS3, VNTR polymorphism of gene IL1RN, I/D polymorphism of CASP8 and mutation GLU342LYS (rs28929474) and GLU264VAL (rs17580) in gene SERPINA1 in patients with various terms of pneumoconiosis formation. Findings are individual criteria of early formation and progress of pneumoconiosis in post-contact period.

The article deals with current and prospective documents on assessment of exposure to noisein crew members of civil aviation aircrafts. The authors suggestedto complete a method calculatingacoustic loadwith correction indexes for uncertainity of measurements concerning noise inside the cabin, for underestimation of noise levels in forced flight regime, forincreased radio talks and active listening time, and for acoustic efficiency of avia-headsets.