Analysis covered work conditions, occupational and cardio-vascular diseases in workers engaged into underground coal extraction. The authors summarized materials on radiation conditions in mines, outlined directions for development of health preservation system for miners, with consideration of WLO recommendations.

Analytic epidemiologic study of mortality covered a cohort of coal miners in Rostov region, who were diagnosed as having occupational disease in various years. The cohort included 9980 individuals. Observation period lasted over 26 years (01/01/1990-31/12/2015). Reference group: adult male population of Rostov region. Consideration covered work conditions, analysis of mortality causes structure in the cohort and general population, calculation of standardized relative risk of death with main nosologic types of diseases. Findings are that the mortality risk in the miners cohort was 1.5-2.2 times higher than the population level, with the causes that are etiologically connected with occupational factors - respiratory diseases, cardio-vascular diseases, malignancies of respiratory organs.

The article present materials on prevalence and features of work conditions with carcinogenic danger, diagnostic value of malignancies in Samara region. The authors necessitate improvement of social hygienic monitoring of work conditions and periodic medical examinations of workers exposed to chemical carcinogens. Suggestions cover main directions to optimize terms and order of sanitary hygienic certificates specification for institutions with carcinogenic danger, improvement of their parameters, better quality of periodic medical examinations of workers exposed to carcinogens.

The article is about studies of some aspects of lifestyle and life quality of pediatric oncologists/hematologists. Positive influence on life quality and lifestyle of pediatric oncologists appeared to result from favorable family conditions - being in official marriage, presence of children have positive influence on life quality and motivation to healthy lifestyle. The doctors relate increased life quality with better living conditions, nutrition quality, medical care, longer leisure, more healthy lifestyle. Oncologists' dissatisfaction with salary result in considerable dual jobholding. The authors suggest that poor maintenance of diagnostic and therapeutic standards, low screening level could be to some extent caused by poor equipment of medical institutions.

Experiments helped to study features of human immune reactivity to long action of occupational hazards - coal stock dust and fluorine compounds. Findings are that coal stock dust inhalation causes activation of urgent adaptation elements at early stage, but by 6^th week of the experiment - chronization of inflammatory process. Fluorine excess, due to its high reactivity, causes mostly toxic effects, early expression of anti-inflammatory cytokines and delayed anti-inflammatory immune response. Main immunologic markers of anthracosilicosis and fluorosis development risk are revealed.

The article presents results of a priori and a posteriori evaluation of occupational risk, based on epidemiologic study of health state among workers of electric steel workshop in Oskol electrometallurgy enterprise, on results of periodic medical examinations with use of medical informational system for improvement of occupational risk management system.

To study influence of vibration factor on cardiovascular system in vibration disease patients with arterial hypertension in late post-contact period, the authors conducted complex structural and functional studies of heart in these patients. The same patients were studied initially and in 6 years of observation. The study covered 12 individuals (average age initially was 45.5±3.0 years). Average length of service with vibration was 17.9±2.9 years. Duration of post-contact period was under 5 years. The examinees were machine assembly workers and riveters assemblers. In vibration disease and arterial hypertension in late post-contact period, there is transformation of left ventricle hyperfunction, mostly by isotonic type, into relatively stable compensation with moderate hypertrophy, with worsened diastolic left ventricle dysfunction both due to active and passive relaxation disorders. Findings also are marked increase of left heart volume, lung artery pressure - that increases load on right ventricle and leads to its diastolic dysfunction.

The article deals with examination results of 713 staffers of RostGMU clinic. Findings are increased intensity of caries, high prevalence of non-carious dental lesions, paradontal and oral mucosa inflammation, in accordance with work conditions. The authors defined structure of morbidity and course peculiarities for main dental diseases in medical staffers subjected to occupational hazards.

The authors presented results of visual fatigue evaluation in therapeutic dentists using operation microscope for endodontic dental treatment, based on questionnaire data, visual physiologic parameters assessment in dependence on illumination level of operative field. Vision disorders are confirmed by results of color successive contrast duration and of critical frequency of flicker fusion.

The authors presented results of X-ray examination of workers subjected to fluorine and its compounds (electrolysis operators, anode workers), workers exposed to vibration at work (fettlers and moulding polishers) and reference group workers. Examination covered males: 50 individuals with suspected fluorosis, 40 individuals with suspected vibration disease, 30 individuals of reference group, matched by age and length of service with main groups. To optimize diagnosis of ostheopathy caused by occupational influences and to solve examination problems, the authors first in X-ray diagnosis of such diseases studied possibilities of objective evaluation of bone tissue stucture transformation by means of X-ray comparametry of limbs bone trabecules.

Study of medical and biologic parameters of manual asymmetry revealed statistically reliable differences and certain correlation relationships of time and quality characteristics of hand movements. The authors calculated asymmetry coefficients that helped to identify individuals with occult left-handedness in performing certain elements of operator work.

Spectrometric methods assessed 25 chemical elements (Al, As, B, Be, Ca, Cd, Co, Cr, Cu, Fe, Hg, I, K, Li, Mg, Mn, Na, Ni, P, Pb, Se, Si, Sn, V, Zn) content of hair in 20 female medical staffers of oncologic dispensary (42,83 ± 2,54 years) and 105 women of reference group (45,96 ± 0,55 years), permenent dwellers of Magadan city. Comparison of the data obtained with reference values of chemical elements concentrations in healthy individuals showed that median concentrations of Ca, Co, Cr, Mg, Se in hair of the examinees are less. There was a deficiency of Ca (58%), Mg and Cu (53%), Co and Zn (47%), Cr and I (26%). Evidence is that increased functional exertion experienced by body element system of medical staffers under complex burden of occupational and environmental factors can eventually cause dysadaptation and gradual development of pathologic states.

Information technologies is one among the most dynamically developing spheres all over the world, but now labour market faces dramatic deficiency of IT-specialists. The study covered totally 50 workplaces: 15 of specialists in IT-sphere and 35 of active users of personal computers - and determined correspondence between workplace dimensions and individual anthropometric characteristics of workers. Diagrams of working postures were set for all the examinees, and goniometric parameters were compared with recommended ranges. Most workplaces studied did not correspond to individual anthropometric data - that resulted in improper working posture. Nearly all goniometric parameters revealed deviations from recommended ranges, none of workers had all 8 or at least 7 goniometric parameters within recommended values. Simple ergonomic measures could provide ergonomic rationality of workplaces, improve working postures of staffers and with this decrease prevalence of locomotory discomfort and increase performance of IT-specialists.

Considerable excess of MAC for acrylonitryl was detected in workplace air of Krasnoyarsk synthetic rubber plant. In 10.8% of workers exposed to such conditions, high levels of serum cancer embryonic antigen were revealed by radioimmune assay, and one fifth of this group were diagnosed as having gastro-intestinal malignances after clinical investigations. Retrospective statistic analysis over 20 years demonstrated that 48% of personnel working in hazardous workships died with various malignancies afterwards. The data obtained prove that industrial monomer acrylonitryl is obligatory human carcinogen.