The authors present results of medical social monitoring of occupational hazards that are the most prevalent in railway occupations workers, statistic data on occupational morbidity of railway transport workers over last 10 years. The article covers major causes of unfavorable effects resulting from occupational hazards in various workers categories. Dynamics of occupational morbidity parameters and its structure concerning separate nosologic entities are analyzed.

The article covers psychophysiologic aspects of work conditions and work safety in train operator occupations of railway transport. The authors consider problems of medical examination, occupational fitness analysis in these individuals if in various diseases or functional disorders.

The article covers hi-tech cardiologic care model in system of medical support of train operation safety, with definition of structure blocks in this model. Discussion covers peculiarities of the model functioning in comparison with the governmental system of hi-tech medical care, including its closed cycle principle characteristics, wide patients selection among railway workers, continuous and close cooperation between various medical speicalities, with active involvement of occupational fitness specialists (medical examination committees of various levels, including Central Medical Examination Committee), major extent of interventional rentgenosurgical technologies applied in diseases without significant functional failure.

The authors studied frequency of various variants of diurnal blood pressure profile, including discordant ones in systolic and diastolic pressure. The article also covers comparative evaluation of diurnal blood pressure profile results, assessed in amulatory and stationery conditions. When analyzing frequency of various types of diurnal blood pressure profile, it's expedient to outline concordant and discordant variants. Optimal concordant variant - dipper - appears in a group of normal blood pressure and early hypertension individuals in less than 50%. Ambulatory diurnal monitoring of blood pressure presents more favorable parameters, vs. that performed in stationery conditions.

The article covers personality characters of locomotive crew workers of Russian Railways JSC, and specifying a block of methods for psychologic support of these workers' occupational activities. According to the results obtained, the authors presented a thorough description of characterologic, motivational personality traits characterizing a select of locomotive crew workers, and analyzed a relationship between the traits and levels of accidents in the workers' occupational activity.

Expert and instrumental assessment covered efficiency of telemechanic system controlling train operators wakefulness in simulation of real night travel, through special simulator complex “Locomotive operator cabin”. The telemechanic system controlling train operators wakefulness, if exploited correctly, provides wakefulness of the train operators at the level sufficient for the effective work. That is supported by distribution of falling asleep cases in experiments with activated or deactivated telemechanic system controlling train operators wakefulness. The study proved efficiency of telemechanic system controlling train operators wakefulness.

The study covered influence of Melaxene on human brain functional state. Complex dynamic (12-hour) neurophysiologic study revealed that single dose of Melaxene (3 mg) influences brain functional state - reliably increases cross-correlation parameters of global spatial synchronization of cortex biopotentials in various ranges of EEG rhythms. Analysis of functional asymmetry of spatial synchronization of cortex biopotentials in various brain areas proved that Melaxene acitvates important cross-correlation links in spatial synchronization of cortex biopotentials in left and right brain hemispheres, with dominated activity of left hemisphere.

The authors considered problems of restructurization and organization of medical examination committees in Russian Railways JSC, and their interlevel interactions. Detailed specification included documents circulation, order and terms of medical examination. Principles of conclusion on occupational fitness examination are specified. The article covers tasks of further development of occupational medical examination work in trade occupational medicine.

The authors determined criteria of medical and psychologic training of railway transport workers, with applied information digital technologies. The results obtained prove that application of software «Railway worker» («Zheleznodorozhnik») reduces frequency and duration of «emotional stress states».

The authors revealed features of metabolic syndrome diagnosis by means of various intradisciplinary criteria in locomotive crew workers. The locomotive crew workers, if compared to mounters, demonstrate 1.4 times more frequent excessive body weight, 1.6 times more frequent obesity, 1.4 times more frequent dyslipidemia, 2 times more common arterial hypertension. According to RSCS, metabolic syndrome in locomotive operators appeared more frequent - 1.6 times than in IDF, 1.5 times than in ATP, ESN. Frequency of metabolic syndrome in males of stress occupations varies from 30% according to ATP, IDF, ESN to 49% according to RSCS - that is 2.5 times more frequent than in individuals with low occupational stress. Bioimpedometry revealed fluids retention in 13% of train operators, water deficit in 24%, muscular mass deficiency in 55%. RSCS criteria are priority in interdisciplinary approach to metabolic syndrome evaluation in males under occupational stress. Assessment of visceral fat in locomotive crew workers helps to formulate purposeful prophylactic recommendations.