The article deals with state of occupational morbidity and principles of occupational medical service organization in Rostov region. The authors justify necessity to create medical rehabilitation departments in occupational pathology centers, partially financed by RF Social Security Fund.

The authors consider results of retrospective analysis of primary consultations of 2791 coal miners with occupational lumbosacral radiculopathy over 1976-2014 in Rostov regional occupational center. Findings are that 975 miners (34.9%) underwent examination of the disease connection with occupation, and occupational lumbosacral radiculopathy was diagnosed on primary consultation, but in 1816 miners (65.1%) recurrent lower back pain and health injury by occupational hazards were diagnosed. Recurrent lower back pain in miners was considered as a predictor of occupational lumbosacral radiculopathy. The authors suggested a way of prevention for occupational lumbosacral radiculopathy and comorbid conditions in miners during periodic medical examinations in occupational pathology center.

The review considers problems of reproductive health disorders in night shift workers. In materials of national and foreign authors, ambiguous opinions are presented on the influence, such as on reproductive sphere malignancies development in shift workers. Data of experimental and clnical laboratory studies are presented, that support reproductive pathologies connected with night shift work. The authors tackle a problem on role of epiphysis and circadian rhythms, that influence physiologic biologic rhythms.

The article deals with obligatory medical examination of drivers (procedure, form of medical conclusion and its release order). The authors consider drivers categories that require obligatory medical examination.

The authors analyzed mortality parameters among occupational disease patients in coal industry over 19682014 (9271 cases). Findings are significant increase in age and length of service in workers first registered in occupational pathology center, and 6-fold decrease of life span from occupational disease diagnosis till death. The authors necessitate specification and implementation of follow-up procedure in workers with high occupational risk and in occupational diseases patients, and complex medical rehabilitation for individuals with primary stage of occupational diseases.

The authors constructed forecasting models of risk for occupational lumbosacral radiculopathy combined with vibration disease and occupational neurosensory deafness in coal miners suffering from lower back pain and signs of occupational hazards influence on health state. Scientific basis covered determination of high and low risk groups for health disorders in miners, according to calculations within suggested formula in forecasting models. Findings are that each year following primary diagnosis of lower back pain and signs of occupational hazards influence on health state, probability of occupational lumbosacral radiculopathy combined with vibration disease increased by 15% (OR = 1.151; 95% CI = 1.105-1.200), combined with occupational neurosensory deafness - by 5% (OR = 1.054, 95% CI = 1.0971.507). Probability to get occupational neurosensory deafness combined with occupational lumbosacral radiculopathy was maximal in miners aged 30-39, and combination of vibration disease and radiculopathy was more frequent in miners aged 40-49 (OR = 1.542; 95% CI = 1.154-2.062).

Comparative analysis covered cardiovascular system state in teachers of primary school, secondary school and additional education in Rostov region educational institutions. Evaluation covered 7 levels of “ideal cardiovascular health” parameters.

The authors analyzed problems of operating system of workers' social security, among them - insurance payments are provided on basis of experts' lists of productions, work types, occupations without consideration of real work conditions on specific workplaces, health state and performance of workers. Solutions of the problems are suggested.

Based on examination of workers exposed to various occupational factors in major industrial enterprises, the authors present results of comparative evaluation of some humoral immunity parameters. According to the study, Ig A, M and G are possible as available indicators in evaluation of functional resources being major risk factors for occupational health. Timely diagnosis and analysis of risk factors help to improve methodology of work groups certification in industrial enterprises, specification of innovation diagnostic tools and rehabilitation of working population.

The article deals with employer's requirements regulating choice and management of respirators use in RF. Considerations include drawbacks of these requirements, their inadequacy to contemporary western standards, and evidences that fulfilment of these requirements fails to reduce risk of polluted air effects towards the safety. The authors demonstrate that decreasing jeopardy class with workers' use of respirators according to legal regulations is unallowable. Recommendations are given to improve requirements for workers' protection against air pollution.

The authors attempted to follow history of national occupational pathology development, analyzed features of its formation of Russian Federation territory, presented main stages and key moments of its establishment in XIX-XXI centuries.