

Hypersensitivity pneumonitis: difficulties of diagnosis and occupational pathological aspects
https://doi.org/10.31089/1026-9428-2025-65-4-271-278
EDN: aouuml
Abstract
Hypersensitivity pneumonitis (HP) is an interstitial lung disease characterized by an immunological reaction of the lung parenchyma in response to certain antigens in a susceptible individual. According to the literature, the prevalence of HP is 1–4 cases per 100 thousand population. Identifying HP is a complex task and requires an integrated approach with the participation of different specialists, since currently there is no "gold standard" for its diagnosis. A clinical observation of a patient with HP that developed against the background of his professional activity is presented. Incomplete taking of the patient's medical history and insufficient consideration of the possible influence of work environment factors on the onset of the disease led to a delay in getting a correct diagnosis and prescribing appropriate treatment.
Contributions:
Pavlyukova M.V. — research concept and design, data collection and processing, text writing, editing;
Tikhomirova O.A. — data collection and processing, editing;
Frangu R.K. — data collection and processing, editing;
Stafeev A.N. — research concept and design, text writing, editing;
Mirzakhamidova S.S. — research concept and design, data collection and processing, editing;
Neklyudova G.V. — concept and design of research, editing;
Rachina S.A. — research concept and design, text writing, editing;
Avdeev S.N. — research concept and design, text writing, editing.
Funding. The study had no funding.
Conflict of interest. The authors declare no conflict of interest.
Received: 27.02.2025 / Accepted: 01.04.2025 / Published: 08.05.2025
About the Authors
Margarita V. PavlyukovaRussian Federation
Resident, Department of Hospital Therapy No. 2, I.M. Sechenov First Moscow State Medical University
e-mail: rita.golynina@mail.ru
Olga A. Tikhomirova
Russian Federation
Head, Therapy Department No. 2, City Clinical Hospital named after S.S. Yudin
e-mail: dr.tihomirova@yandex.ru
Raisa K. Frangu
Russian Federation
Therapist, Department of Therapy No. 2, City Clinical Hospital named after S.S. Yudin
e-mail: raya.frangu@mail.ru
Alexandr N. Stafeev
Russian Federation
Assistant, Department of Hospital Therapy No. 2, I.M. Sechenov First Moscow State Medical University
e-mail: stafeev_a_n@staff.sechenov.ru
Svetlana S. Mirzakhamidova
Russian Federation
Deputy Chief Physician for Medical Affairs, City Clinical Hospital named after S.S. Yudin
e-mail: rimatevs@mail.ru
Galina V. Neklyudova
Russian Federation
Professor, Department of Pulmonology, I.M. Sechenov First Moscow State Medical University, Dr. of Sci. Med
e-mail: neklyudova_g_v@staff.sechenov.ru
Svetlana A. Rachina
Russian Federation
Head, Department of Hospital Therapy No. 2, I.M. Sechenov First Moscow State Medical University, Dr. of Sci. Med., Professor
e-mail: rachina_s_a@staff.sechenov.ru
Sergey N. Avdeev
Russian Federation
Head of the Department of Pulmonology, I.M. Sechenov First Moscow State Medical University, Dr. of Sci. Med., Professor, Academician of the Russian Academy of Sciences
e-mail: avdeev_s_n@staff.sechenov.ru
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Review
For citations:
Pavlyukova M.V., Tikhomirova O.A., Frangu R.K., Stafeev A.N., Mirzakhamidova S.S., Neklyudova G.V., Rachina S.A., Avdeev S.N. Hypersensitivity pneumonitis: difficulties of diagnosis and occupational pathological aspects. Russian Journal of Occupational Health and Industrial Ecology. 2025;65(4):271-278. (In Russ.) https://doi.org/10.31089/1026-9428-2025-65-4-271-278. EDN: aouuml