Improvement of criteria and methods for assessing the functional state and factors of the labor process based on a personalized approach

Introduction. Prolonged exposure to the factors of nervous and stressful mental labor forms unfavorable stress conditions of physiological systems, increasing the risk of developing occupational diseases, including pathology of the cardiovascular system. Numerous studies devoted to the study of the functional state have not revealed a sufficiently unified approach to its assessment, which determines the relevance of this work.

The study aims to develop criteria and methods for assessing the functional state and factors of the labor process of workers in neuropsychiatric labor, taking into account people of different age groups to preserve health and labor potential.

Materials and methods. The researchers assessed the functional state according to pre-shift medical control data on professional groups of ground transport drivers and employees of locomotive crews of Russian Railways, which were selected and analyzed based on gender and age differences. According to the indicators of heart rate, blood pressure, scientists calculated the production parameters of hemodynamics (peripheral resistance, minute volume), indices of the cardiovascular system (Index of Functional Changes, Myznikov index, Kerdo vegetative index), which revealed a close correlation with age. The authors carried out statistical processing of the obtained data using IBM SPSS Statistics 26 software.

Results. Based on the database of pre-trip medical examinations, specialists have developed a model for the step-by-step geometric construction of nonlinear fluctuations of the cardiovascular system, which allows us to assess and predict the functional state of a person, the degree of disturbance of vegetative balance, and the risks of developing pathology in the cardiovascular system. Based on the parameters of the digital profiles of employees, taking into account gender and age characteristics, new algorithms for assessing the functional state for monitoring the working capacity of employees were introduced into the existing digital information system of the Institute's Medical Information System.

Conclusion. The researchers have developed a criterion apparatus and a set of methods for assessing the indicators of the functional state of the body (according to the indicators of the cardiovascular system) in conditions of neuro-emotional labor activity, taking into account the influence of factors of tension and severity of the labor process on the health of workers (risks of arterial hypertension) of various gender and age groups in modern conditions. Based on the results of comprehensive studies of workers in neuropsychiatric mental labor, the standards of work intensity were improved, and the authors proposed a new version of the indicator "Work with information load and creative content (% of shift time)".

Limitations. There are limitations due to the peculiarities of collecting (obtaining) physiological data during pre-trip medical examinations.

Ethics. The study was approved by the local Ethical Committee of Izmerov Research Institute of Occupational Health (protocol No. 1 of February 16, 2022).

Contributions:
Glukhov D.V. — concept and design of the study;
Yushkova O.I. — text writing, editing;
Kapustina A.V. — collecting and processing material, text writing;
Forverts A.Yu. — collection and processing of material, editing.

Funding. The study had no funding.

Conflict of interest. The authors declare no conflict of interest.

Received: 03.04.2025 /Accepted: 04.04.2025 / Published: 08.05.2025

1. Matyuhin V.V., Buhtiyarov I.V., Shardakova E.F. et al. The role of labor physiology in preserving working capacity and health in workers of various types of labor activity. Achievements and prospects of development. Med. truda i prom. ekol. 2013; 6: 19–24 https://elibrary.ru/qiutwj (in Russian).

2. Smirnov K.M. Labor intensity. Uspekhi Fiziologicheskih nauk. 1984; 1: 76–99 (in Russian).

3. Sorokin G.A. Standardization of labor intensity by its duration, density and pace. Med. truda i prom. ekol. 2001; 10: 28–32 (in Russian)

4. Novozhilova A.A., Geregei A.M., Merkulova A.G. Features of the study of occupational fatigue in labor physiology. Med. truda i prom. ekol.2022; 62(4): 238–246 https://doi.org/10.31089/1026-9428-2022-62-4-238-246 (in Russian).

5. Trifonov V.V. Autonomic reactivity in individuals with different types of baseline autonomic tone during mental workload under stress. Sovremennye voprosy biomediciny. 2023; 7(3): 26–29 https://doi.org/10.24412/2588-0500-2023_07_03_17 (in Russian).

6. Akimova E.V., Kayumova M.M., Bessonova M.I. Psychosocial risk factors for the development of cardiovascular diseases in female populations from the perspective of anxiety research. Russian Journal of Preventive Medicine. 2022; 25(7): 100-105 https://elibrary.ru/fystqz https://doi.org/10.17116/profmed202225071100 (in Russian).

7. Occupational stress and Workers Health. Book of abstracts XIV conference on occupational Health. China; 1984.

8. Sorokin G.A., Chistyakov N.D. Duration of production-related fatigue as a criterion for assessing workload and the cause of chronic diseases in workers. Med. truda i prom. ekol. 2022; 62(9): 594–600 https://doi.org/10.31089/1026-9428-2022-62-9-594-600 (in Russian).

9. Sudakov K.V. Mechanisms of congestive changes in the limbic-reticular structures of the brain during emotional stress. Psychoemotional stress. Moscow, Russian Academy of Medical Sciences, Regional International Center for Stress Prevention; 192.

10. Drapkina O.M., Fedin A.I., Dorofeeva O.A., Medvedev V.E., Kareva E.N., Dzhioeva O.N. et al. Influence of psychosocial risk factors on the course and prognosis of cardiovascular diseases. Kardiovaskulyarnaya terapiya i profilaktika. 2022; 21(5): 3280 https://doi.org/10.15829/1728-8800-2022-3280 (in Russian).

11. Zhidkova E.A., Shlipakov S.V., Gutor E.M. et al. Prevalence of exceeding normative values of blood pressure in workers of locomotive brigades according to the results of multiyear dynamics of pre-trip medical examination. Kardiovaskulyarnaya terapiya i profilaktika. 2022; 21(5): 6–12 https://doi.org/10.15829/1728-8800-2022-3189 (in Russian).

12. Wu W.T., Tsai S.S., Wang C.C., Lin Y.J., Wu T.N., Shih T.S. et al Professional Driver's Job Stress and 8-year Risk of Cardiovascular Disease: The Taiwan Bus Driver Cohort Study. Epidemiology. 2019; 30: 39–47. https://doi.org/10.1097/EDE.0000000000001003

13. Nevskaya Yu.M. Clinical characteristics of neurotic disorders in long-distance telephone operators. Gigiena truda i profzabolevaniya. 1996; 2: 30–32 (in Russian).

14. Guest A.J., Clemes S.A., King J.A. et al. Attenuated cardiovascular reactivity is related to higher anxiety and fatigue symptoms in truck drivers. Psychophysiology. 2021; 58(9): 13–17. https://doi.org/10.1111/psyp.13872

15. Cheung C.K.Y., Tsang S.S.L., Ho O. et al. Cardiovascular risk in bus drivers. Hong Kong Med. J. 2020; 26(5): 451–456. https://doi.org/10.12809/hkmj198087

16. Kazidaeva E.N., Sergunina I.N., Venevceva Yu.L. Risk factors of cardiovascular diseases and their dynamics in locomotive crew workers. Kardiovaskulyarnaya terapiya i profilaktika. 2018; 17(3): 53–58 https://doi.org/10.15829/1728-8800-2018-3-53-58 https://elibrary.ru/xsrool (in Russian).

17. Minenko I.A., Shahmatova S.A. 4P-medicine in sanatorium-resort treatment of patients after acute circulatory failure. Vrach skoroj pomoshchi. 2021; 7: 51–60.

18. Terkola R., Antonanzas F., Postma M. Economic evaluation of personalized medicine: a call for real-world data. Eur. J. Health Econ. 2017; 18(9): 1065–1067. https://doi.org/10.1007/s10198-017-0890-x

19. Crawley F.P. Personalised Medicine and the Role of Patients in Healthcare and Health Research in Europe. Journal of Health Development. 2019; 1(30): 33–36.

20. R 2.2.2006-05. Guide on Hygienic Assessment of Factors of Working Environment and Work Load. Criteria and Classification of Working Conditions. M.; 2005 (in Russian).

21. Buhtiyarov I.V., Matyuhin V.V., Yushkova O.I. et al. Method of determining the functional stress of the human organism under mental and nervous-emotional loads: pat. 2546089 Ros. Federaciya: MPK51 A61V 10/00; №2013152288 https://elibrary.ru/acnwff (in Russian).

22. Methodical recommendations for the assessment of physiological norms of human body tension, taking into account gender differences, at different types of labor activity (mental, visual and physical). Approved by the Scientific Council No. 45 on medical and environmental problems of health of working people. М., 2015 (in Russian).

23. Zakharova M.A., Merkulova A.G., Kalinina S.A. Study of the influence of age on hemodynamic parameters and heart rate variability in female streetcar drivers. In: Proceedings of the 17th Russian National Congress with international participation "PROFESSION and HEALTH", September 26-29, 2023, Nizhny Novgorod. M.: NKO AMT, Izmerov Research Institute of Occupational Health; 2023 https://doi.org/10.31089/978-5-6042929-1-4-2023-1-185-189 (in Russian).

24. Optimization of the functional state of the organism in the physical culture and health center of an industrial enterprise: Methodical recommendations. Ed. by R.M. Baevsky. М., 1988 (in Russian).

25. Glukhov D.V., Yushkova O.I., Kapustina A.V., Forwerts A.Yu., Kostenko N.A. Physiological assessment of the functional state of workers in neuro-emotional labor of different ages according to the results pre-shift control. Med. truda i prom. ekol. 2024; 63(6): 378–386 https://doi.org/10.31089/1026-9428-2024-64-6-378-386 https://elibrary.ru/vjpooz (in Russian).

26. Matyukhin V.V., Tarasova L.A., Yushkova O.I. et al. Physiological substantiation of the norms of body tension at different types of labor activity. Actual problems of labor medicine: Proceedings of the Research Institute of MT RAMS. М.; 2001 (in Russian).