Immune and genetic changes in workers exposed to industrial noise and dust
Abstract
Comparative analysis covered immune genetic parameters in nonferrous metallurgy workers. The authors demonstrated differences in immune genetic profile between male and female workers, under exposure to combination of occupational hazards: noise and dust. Analysis of gene polymorphism revealed predominant disorders in the female workers, concerning criterion of prevalence for minor allele of genes in 1 and 2 phases of detoxication, neuro-endocrine regulation, lipid and energy metabolism, genes of immune regulation and apoptosis.
About the Authors
O. V. Dolgikh
FBSI «Federal Scientific Center for Medical and Preventive Health Risk Management Technologies»; FSBEI of Higher Professional Education «Perm State National Research University»; FSBEI of Higher Education «Perm National Research Polytechnic University»
Russian Federation
Russian Federation
A. V. Krivtsov
FBSI «Federal Scientific Center for Medical and Preventive Health Risk Management Technologies»
Russian Federation
Russian Federation
K. G. Starkova
FBSI «Federal Scientific Center for Medical and Preventive Health Risk Management Technologies»
Russian Federation
Russian Federation
O. A. Boubnova
FBSI «Federal Scientific Center for Medical and Preventive Health Risk Management Technologies»
Russian Federation
Russian Federation
D. G. Dianova
FBSI «Federal Scientific Center for Medical and Preventive Health Risk Management Technologies»
Russian Federation
Russian Federation
N. A. Vdovina
FBSI «Federal Scientific Center for Medical and Preventive Health Risk Management Technologies»
Russian Federation
Russian Federation
V. M. Uhabov
State Budget Educational Institution of Higher Professional Education «Perm State Medical University named after E.A. Vagner»
Russian Federation
Russian Federation
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Review
For citations:
Dolgikh O.V., Krivtsov A.V., Starkova K.G., Boubnova O.A., Dianova D.G., Vdovina N.A., Uhabov V.M. Immune and genetic changes in workers exposed to industrial noise and dust. Russian Journal of Occupational Health and Industrial Ecology. 2015;(12):21-25. (In Russ.)
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