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Russian Journal of Occupational Health and Industrial Ecology

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Certain candidate genes polymorphic variants impact in the development of hypertension when exposed to vinyl chloride

https://doi.org/10.31089/1026-9428-2019-59-9-667-668

Abstract

It was found that in persons exposed by vinyl chloride, the risk of hypertension increases six times in carriers of the genotype C/C polymorphic variant of Leu28Pro gene APO E, 9.5 times - in carriers of the genotype T/T polymorphic variant C786T gene eNOS3 and 1.75 times - in carriers of the genotype T/C polymorphic variant Met 235 Thr gene AGT.

About the Authors

I. V. Kudaeva
East-Siberian Institute of Medical and Ecological Research
Russian Federation


O. A. Dyakovich
East-Siberian Institute of Medical and Ecological Research
Russian Federation


I. M. Eshchina
East-Siberian Institute of Medical and Ecological Research
Russian Federation


Review

For citations:


Kudaeva I.V., Dyakovich O.A., Eshchina I.M. Certain candidate genes polymorphic variants impact in the development of hypertension when exposed to vinyl chloride. Russian Journal of Occupational Health and Industrial Ecology. 2019;(9):667-667. (In Russ.) https://doi.org/10.31089/1026-9428-2019-59-9-667-668

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ISSN 1026-9428 (Print)
ISSN 2618-8945 (Online)