Biological risk factor of occupational morbidity with tuberculosis among medical professionals
https://doi.org/10.31089/1026-9428-2018-8-52-57
Abstract
The article presents molecular genetic characteristics of M. tuberculosis circulating in Omsk region, as a biologic risk factor of tuberculosis morbidity among medical institutions workers. The authors used descriptive method of epidemiologic study, method of MIRUVNTR-typing of M. tuberculosis DNA. Findings are M. tuberculosis stains of Beijing genotype with VNTR-profile 233325173533424, isolated out of tuberculosis patients cluster being under stationary treatment. 65.2% of the stains had multiple drug-resistance to anti-tuberculosis medications. Respiratory tuberculosis was diagnosed in 85.4% of the cases, extra-pulmonary tuberculosis (urinary system, peripheral lymph nodes, eyes, CNS tuberculosis) equaled 14.6%. Nearly 30% of tuberculosis cases in the health care workers were associated with the bacterioexcretion.
About the Authors
O. A. Pasechnik
Omsk State Medical University
Russian Federation
8, Ak. Lavrentieva Ave., Novosibirsk, 630090
Russian Federation
8, Ak. Lavrentieva Ave., Novosibirsk, 630090
O. V. Plotnikova
Omsk State Medical University
Russian Federation
8, Ak. Lavrentieva Ave., Novosibirsk, 630090
Russian Federation
8, Ak. Lavrentieva Ave., Novosibirsk, 630090
V. L. Stasenko
Omsk State Medical University
Russian Federation
8, Ak. Lavrentieva Ave., Novosibirsk, 630090
Russian Federation
8, Ak. Lavrentieva Ave., Novosibirsk, 630090
M. A. Dymova
Institute of Chemical Biology and Fundamental Medicine;
Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences
Russian Federation
Russian Federation
10, Ak. Lavrentieva Ave., Novosibirsk, 630090
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Review
For citations:
Pasechnik O.A., Plotnikova O.V., Stasenko V.L., Dymova M.A. Biological risk factor of occupational morbidity with tuberculosis among medical professionals. Russian Journal of Occupational Health and Industrial Ecology. 2018;(8):52-57. (In Russ.) https://doi.org/10.31089/1026-9428-2018-8-52-57
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