INFLUENCE OF «CYTOREACTOR-DIHYDROQUERCETIN» ADAPTOGEN ON ACTIVITY OF ENERGY METABOLISM SERUM ENZYMES UNDER CHRONIC EXPOSURE TO COAL STOCK DUST (experimental study).
https://doi.org/10.31089/1026-9428-2018-6-23-28
Abstract
Using «Cytoreactor-dihydroquercetin» adaptogen for long inspiration of coal stock dust normalizes metabolic processes, decreases dystrophic changes and prevents formation liver necrosis.
Keywords
coal stock dust,
prevention,
adaptogen,
succinic acid,
dihydroquercetin,
energy metabolism,
blood,
liver
About the Authors
A. G. Zhukova
Research Institute for Complex Problems of Hygiene and Occupational Diseases;
Novokuznetsk Institute (Branch) of Kemerovo State University
Russian Federation
Russian Federation
ул. Кутузова, 23, Новокузнецк, 654041
N. N. Zhdanova
Research Institute for Complex Problems of Hygiene and Occupational Diseases
Russian Federation
23, Tsiolkovskogo str., Novokuznetsk, Russian Federation, 654041
Russian Federation
23, Tsiolkovskogo str., Novokuznetsk, Russian Federation, 654041
T. D. Logunova
Research Institute for Complex Problems of Hygiene and Occupational Diseases
Russian Federation
Russian Federation
ул. Кутузова, 23, Новокузнецк, 654041
N. V. Kizichenko
Research Institute for Complex Problems of Hygiene and Occupational Diseases;
Novokuznetsk Institute (Branch) of Kemerovo State University
Russian Federation
23, Tsiolkovskogo str., Novokuznetsk, Russian Federation, 654041
Russian Federation
23, Tsiolkovskogo str., Novokuznetsk, Russian Federation, 654041
M. S. Bugaeva
Research Institute for Complex Problems of Hygiene and Occupational Diseases;
Novokuznetsk State Institute for Further Training of Physicians — Branch Campus of Russian Medical Academy of Continuous Professional Education
Russian Federation
Russian Federation
5, Stroiteley ave., Novokuznetsk, Russian Federation, 654005
References
1. Zhukova A.G., Ulanova E.V., Fomenko D.V., Kazickaya A.S., Yadykina T.K. Specificity of cellular response to action of various occupational toxicants. Med. truda i prom. ekol. 2011; 7: 23–6 (in Russian).
2. Panev N.I., Korotenko O.Yu., Filimonov S.N., Burdejn A.V., Ambrosova M.O. Structural and functional changes in myocardium at rest and after exertion test in patients with dust bronchitis combined with coronary heart disease and arterial hypertension. Med. truda i prom. ekol. 2009; 11: 43–8 (in Russian).
3. Lukyanova L.D. Signal function of mitochondria in hypoxia and adaptation. Patogenez. 2008; 6; 3: 4–12 (in Russian).
4. Maevskij E.I., Uchitel M.L., Grishina E.V. Ammonium succinate — alternative to antioxidants? www.medline.ru Biofizika. 2010; 11 (8): 78–92 (in Russian).
5. Bizyuk L.A., Korolevich M.P. Antioxidant dihydroquercetin: clinical pharmacologic efficiency and synthesis ways. Lechebnoe delo. 2013; 1 (29): 13–9 (in Russian).
6. Tregubova I.A., Kosolapov V.A., Spasov A.A. Antioxidants: contemporary state and prospects. Uspehi fiziologicheskih nauk. 2012; 43(1): 75–94 (in Russian).
7. Zaharenkov V.V., Mihajlova N.N., Gorohova L.G., Romanenko D.V., Zhukova A.G., Bugaeva M.S., Bondarev O.I. Method of prevention of anthracosilicosis in experimental simulation. Patent RF RUS 2611935; registration date 29.01.2016; published 01.03.2017; Byul. №7 (in Russian).
8. Nersesova L.S. Role of creatinkinase and its substrates in central nervous system in normal and pathologic states. Zhurnal evolyucionnoj biohimii i fiziologii. 2011; 47(2): 120–7 (in Russian).
9. Kola B., Boscaro M., Rutter G.A., Grossman G.A., Korbonits M. Expanding role of AMPK in endocrinology. Trends Endocrinol. Metab. 2006; 17: 205–15.
10. Fokina E.G., Roslyj I.M. Enzymologic part of biochemical human pasport. Med. alfavit. Epidemiologiya i gigiena, 2013; 4: 34–6 (in Russian).
11. Shemarova I.V., Nesterov V.P., Korotkov S.M., Silkin Yu.A. Evolution aspects of cardioprotection. Zhurnal evolyucionnoj biohimii i fiziologii. 2018; 54(1): 9–19 (in Russian).
12. Wiedemann A., Johnson R.S. Biology of HIF–1α. Cell Death and Differentiation. 2008; 15: 621–7.
13. Lebedko O.A., Ryzhavskij B.Ya., Demidova O.V. Influence of echinochrome A antioxidant on pneumofibrosis induced by bleomycin. Byulleten eksperimentalnoj biologii i mediciny. 2015; 159(3): 329–332 (in Russian).
14. Zaharenkov V.V., Mihajlova N.N., Zhdanova N.N., Gorohova L.G., Zhukova A.G. Experimental study of mechanisms underlying cardiomyocytes’ intracellular defense associated with phases of anthracosilicosis development. Byulleten eksperimentalnoj biologii i mediciny. 2015; 159(4): 418–22 (in Russian).
Review
For citations:
Zhukova A.G., Zhdanova N.N., Logunova T.D., Kizichenko N.V., Bugaeva M.S. INFLUENCE OF «CYTOREACTOR-DIHYDROQUERCETIN» ADAPTOGEN ON ACTIVITY OF ENERGY METABOLISM SERUM ENZYMES UNDER CHRONIC EXPOSURE TO COAL STOCK DUST (experimental study). Russian Journal of Occupational Health and Industrial Ecology. 2018;(6):23-28. (In Russ.) https://doi.org/10.31089/1026-9428-2018-6-23-28
Views:
742
Email this article 
