Clinical and radiological manifestations of silicotuberculosis
https://doi.org/10.31089/1026-9428-2018-5-14-18
Abstract
The authors analysed clinical and radiologic signs in 32 silicotuberculosis patients who equalled to 12.6% of 252 pneumoconiosis patients observed in pulmonology hospital. Among the silicituberculosis patients, the diagnosis was primary in 88% (28/32). In other cases, tuberculosis was a complication of previously diagnosed silicosis (2/32), or silicosis developed on background of formerly inactive tuberculosis (2/32). The silicotuberculosis was presented mostly with local forms of tuberculosis (56%, 18/32) and nodular+nodular interstitial forms of silicosis (66%, 21/32). Changed respiratory function was seen in 63% (20/32) of the patients, with prevailing (41%, 13/32) obstructive type disorders. Follow-up during 2.4×0.4 years revealed lower diffusion ability of lungs and pulmonary hypertension and corpulmonale formation according to echocardiography — that could result from progression both of silicosis and meta-tuberculous pneumofi brosis. Suggestions are to monitor diffusion ability of lungs and echocardiographic parameters for evaluation of silicotuberculosis progression degree.
About the Authors
G. P. OrlovaRussian Federation
6–8, L’va Tolstogo str., St. Petersburg, 197022
N. S. Yakovleva
Russian Federation
6–8, L’va Tolstogo str., St. Petersburg, 197022
E. Yu. Ornitsan
Russian Federation
4, 2nd Sovetskaya str., St. Petersburg, 191036
References
1. Artemova L.V., Baskova N.V., Burmistrova T.B., et al. Federal clinical recommendations on diagnosis, treatment and prevention of pneumoconiosis // Med. truda i prom. ekol. — 2016. — 1. — Р. 36–48 (in Russian).
2. Zaharenkov V.V. Morozova O.A., Viblaya I.V. // Byulleten VSNC SO RA MN. — 2012. — 5 (87). — Chast 2Р. 82–85 (in Russian).
3. Shpagina L. A., Artamonova V.G., Fishman B.B., et al. Pneumoconiosis. Classification. Epidemiology. Pathogenesis. In: N.F. Izmerov, A.G. Chuchalin, eds. Occupational diseases of respiratory organs. National manual. — Moscow: GEOTARMedia, 2015. — Сhap 10. — Р. 363–488 (in Russian).
4. Farazi A, Jabbarias M. Silico-tuberculosis and associated risk factors in central province of Iran // Pan Afr Med J. — 2015. — V20. — P. 333–340.
5. Hnizdo E., Murray J. Risk of pulmonary tuberculosis relative to silicosis and exposure to silica dust in South African gold miners // Occup Environ Med. — 1998. — V. 55. — P. 496–502.
6. Occupational Diseases: Manual: Translated from the Ukrainian / I. Kostyuk, V. Kapustnyk. — Kharkiv: Osnova, 2005. — 400 p.
7. Snider DE Jr. The relationship between tuberculosis and silicosis // Am Rev Respir Dis. — 1978. — V118. № 3. — P. 455–460 [PMID: 707873. DOI: 10.1164/arrd.1978.118.3.455].
8. Zislin DM, Goldelman AG. Current status of the problem of the treatment of silicosis and silicotuberculosis // Gig. Tr. Prof. Zabol. — 1963. — № 7. — P. 39–44.
Review
For citations:
Orlova G.P., Yakovleva N.S., Ornitsan E.Yu. Clinical and radiological manifestations of silicotuberculosis. Russian Journal of Occupational Health and Industrial Ecology. 2018;(5):14-18. (In Russ.) https://doi.org/10.31089/1026-9428-2018-5-14-18