Endothelial dysfunction and nonspecifi c immune reactions in development and progression of osteoarthrosis in women engaged into manual work
Abstract
The article considers mechanisms of development and progression of osteoarthrosis as an occupationally conditioned disease in women of manual work. Women working in physical overstrain conditions are under occupational risk with dysfunction of many body systems. The authors set a hypothesis on association of endothelial dysfunction markers dysbalance and structural remodelling of cartilage matrix as a proof of degenerative changes.
About the Authors
N. N. MaliutinaRussian Federation
26, Petropavlovskaia str., Perm, 614000
M. S. Nevzorova
Russian Federation
26, Petropavlovskaia str., Perm, 614000
References
1. Gazieva I.A. // Klinicheskaya laboratornaya diagnostika. — 2013. — 9. — Р. 119 (in Russian).
2. Izmerov N.F. // Industr. med. — 2003. — 5. — Р. 1–6 (in Russian).
3. Izmerov N.F. // Industr. med. — 2011. — 10. — Р. 2–6 (in Russian).
4. Nevzorova M.S. // Permskiy meditsinskiy zhurnal. — 2012. — 1. — Р. 60–64 (in Russian).
5. Manual on hygienic evaluation working environment and working process factors. Criteria and classifi cation of work conditions. R 2.2.2006–05 (approved by Chief State RF sanitary health offi cer on 29 July 2005) . — Moscow, 2005 (in Russian).
6. Shoybonov B.B. // Klinicheskaya laboratornaya diagnostika. — 2013. — 9. — Р. 50 (in Russian).
7. Yushkova O.I., Matyukhin V.V., Bukhtiyarov I.V., Poroshenko A.S., Kapustina A.V., Kalinina S.A., Lagutina G.N. // Industr. med. — 2014. — 1. — Р. 8–13 (in Russian).
Review
For citations:
Maliutina N.N., Nevzorova M.S. Endothelial dysfunction and nonspecifi c immune reactions in development and progression of osteoarthrosis in women engaged into manual work. Russian Journal of Occupational Health and Industrial Ecology. 2015;(8):38-42. (In Russ.)