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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zurniimtpe</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина труда и промышленная экология</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Occupational Health and Industrial Ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1026-9428</issn><issn pub-type="epub">2618-8945</issn><publisher><publisher-name>FSBSI “Izmerov Research Institute of Occupational Health”</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">zurniimtpe-661</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Лечение больных псориазом с сопутствующим метаболическим синдромом препаратами биологической терапии: предикторы эффективности и потенциальные риски (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Preparations in treatment of psoriasis patients with concurrent metabolic syndrome: efficiency predictors and potential risks (review of literature)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Росете-Пидаль</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Rosete-Pidal</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">org@cgma.su</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Круглова</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kruglova</surname><given-names>L. S.</given-names></name></name-alternatives><email xlink:type="simple">kruglovals@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Понич</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ponich</surname><given-names>E. S.</given-names></name></name-alternatives><email xlink:type="simple">org@cgma.su</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чорбинская</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chorbinskaja</surname><given-names>S. A.</given-names></name></name-alternatives><email xlink:type="simple">kaffizio@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Филатова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Filatova</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">kaffizio@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ ДПО «Центральная государственная медицинская академия» Управления делами Президента РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central state medical academy of department of presidential affairs of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>01</day><month>08</month><year>2017</year></pub-date><volume>0</volume><issue>8</issue><fpage>33</fpage><lpage>36</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Росете-Пидаль Е.А., Круглова Л.С., Понич Е.С., Чорбинская С.А., Филатова Е.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Росете-Пидаль Е.А., Круглова Л.С., Понич Е.С., Чорбинская С.А., Филатова Е.В.</copyright-holder><copyright-holder xml:lang="en">Rosete-Pidal E.A., Kruglova L.S., Ponich E.S., Chorbinskaja S.A., Filatova E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.journal-irioh.ru/jour/article/view/661">https://www.journal-irioh.ru/jour/article/view/661</self-uri><abstract><p>В обзоре освещены литературные данные о лечении больных псориазом с коморбидным метаболическим синдромом препаратами генно-инженерной биологической терапии (ГИБТ). Особое внимание уделено показаниям к назначению ГИБТ, дифференцированному подбору препаратов данной категории больных для снижения рисков ухудшения заболевания.</p></abstract><trans-abstract xml:lang="en"><p>The review covers literature data on treatment of psoriasis patients with concurrent metabolic syndrome by genetic engineering preparations of biologic therapy. Special attention is paid to indications for genetic engineering preparations of biologic therapy, differential selection of such preparations for patients to decrease risks of the disease deterioration.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>псориаз</kwd><kwd>коморбидности</kwd><kwd>метаболический синдром</kwd><kwd>генно-инженерная биологическая терапия</kwd><kwd>psoriasis</kwd><kwd>comorbidity</kwd><kwd>metabolic syndrome</kwd><kwd>genetic engineering preparations of biologic therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бутрова С.А., Дзгоева Ф.Х. Висцеральное ожирение - ключевое звено метаболического синдрома // Ожирение и метаболизм. - 2004. - № 1. - С. 10-16</mixed-citation><mixed-citation xml:lang="en">Бутрова С.А., Дзгоева Ф.Х. 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