<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zurniimtpe</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина труда и промышленная экология</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Occupational Health and Industrial Ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1026-9428</issn><issn pub-type="epub">2618-8945</issn><publisher><publisher-name>FSBSI “Izmerov Research Institute of Occupational Health”</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">zurniimtpe-445</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Структура аллостатической нагрузки у работников железнодорожного транспорта</article-title><trans-title-group xml:lang="en"><trans-title>Structure of allostatic load in railway workers</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горохова</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorokhova</surname><given-names>S. G.</given-names></name></name-alternatives><email xlink:type="simple">cafedra2004@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пфаф</surname><given-names>В. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Pfaf</surname><given-names>V. F.</given-names></name></name-alternatives><email xlink:type="simple">kcrzd@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мурасеева</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Muraseyeva</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">docturmur@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ахсанова</surname><given-names>Э. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Akhsanova</surname><given-names>E. R.</given-names></name></name-alternatives><email xlink:type="simple">phrenik@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пригоровская</surname><given-names>Т. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Prigorovskaya</surname><given-names>T. S.</given-names></name></name-alternatives><email xlink:type="simple">prig-tatyana@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Атьков</surname><given-names>О. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>At'kov</surname><given-names>O. Yu.</given-names></name></name-alternatives><email xlink:type="simple">nkcrzd@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научный клинический центр ОАО «Российские железные дороги»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Clinical Center of Russian Railways</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российская медицинская академия последипломного образования</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Postgraduate Education</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>01</day><month>04</month><year>2016</year></pub-date><volume>0</volume><issue>4</issue><fpage>5</fpage><lpage>9</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Горохова С.Г., Пфаф В.Ф., Мурасеева Е.В., Ахсанова Э.Р., Пригоровская Т.С., Атьков О.Ю., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Горохова С.Г., Пфаф В.Ф., Мурасеева Е.В., Ахсанова Э.Р., Пригоровская Т.С., Атьков О.Ю.</copyright-holder><copyright-holder xml:lang="en">Gorokhova S.G., Pfaf V.F., Muraseyeva E.V., Akhsanova E.R., Prigorovskaya T.S., At'kov O.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.journal-irioh.ru/jour/article/view/445">https://www.journal-irioh.ru/jour/article/view/445</self-uri><abstract><p>В работе изучена аллостатическая нагрузка у работников железнодорожного транспорта как показатель влияния стресса. Проанализированы биомаркеры, образующие индекс аллостатической нагрузки (ИАН), их соотношение при разном уровне ИАН. Выявлено преобладание умеренной аллостатической нагрузки в группе обследованных. Определено, что наибольший вклад в ИАН вносит систолическое и диастолическое АД, общий холестерин и гемоглобин. Проведено сравнение моделей расчета ИАН при разном наборе биомаркеров.</p></abstract><trans-abstract xml:lang="en"><p>The authors studied allostatic load in railway workers, as an indicator of stress effect. Analysis covered biomarkers that form allostatic load index, and their ratio for variable allostatic load index levels. Moderate allostatic load appeared to prevail in the examinees group. Findings are that systolic and diastolic blood pressure, general cholesterol and hemoglobin make major contribution into allostatic load index. Comparison covered models of allostatic load index calculation for variable biomarkers sets.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>аллостаз</kwd><kwd>аллостатическая нагрузка</kwd><kwd>биомаркеры</kwd><kwd>медицина труда</kwd><kwd>allostasis</kwd><kwd>allostatic load</kwd><kwd>biomarkers</kwd><kwd>occupational medicine</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Beckie T.M. A Systematic Review of Allostatic Load, Health, and Health Disparities // Biological Research for Nursing.- 2012.- 14(4).- Р 311-346.</mixed-citation><mixed-citation xml:lang="en">Beckie T.M. A Systematic Review of Allostatic Load, Health, and Health Disparities // Biological Research for Nursing.- 2012.- 14(4).- Р 311-346.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Borrell L.N., Dallo F.J., Nguyen N. Racial/ethnic disparities in all - cause mortality in U.S. adults: The effect of allostatic load // Public Health Reports.- 2010.- 125: 810-816.</mixed-citation><mixed-citation xml:lang="en">Borrell L.N., Dallo F.J., Nguyen N. Racial/ethnic disparities in all - cause mortality in U.S. adults: The effect of allostatic load // Public Health Reports.- 2010.- 125: 810-816.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Clark M.S., Bond M.J., Hecker J.R. Environmental stress, psychological stress and allostatic load // Psychol. Health Med.- 2007.- 12.- Р 18.</mixed-citation><mixed-citation xml:lang="en">Clark M.S., Bond M.J., Hecker J.R. Environmental stress, psychological stress and allostatic load // Psychol. Health Med.- 2007.- 12.- Р 18.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Dich N., Lange T., Head J., Rod N.H. Work stress, caregiving, and allostatic load: prospective results from the Whitehall II cohort study // Psychosom Med.- 2015.- 77(5).- Р. 539-47.</mixed-citation><mixed-citation xml:lang="en">Dich N., Lange T., Head J., Rod N.H. Work stress, caregiving, and allostatic load: prospective results from the Whitehall II cohort study // Psychosom Med.- 2015.- 77(5).- Р. 539-47.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Dowd J.B., Simanek A.M., Aiello A.E. Socio - economic status, cortisol and allostatic load: a review of the literature // Int J Epidemiol.- 2009.- 38(5).- Р 1297-309.</mixed-citation><mixed-citation xml:lang="en">Dowd J.B., Simanek A.M., Aiello A.E. Socio - economic status, cortisol and allostatic load: a review of the literature // Int J Epidemiol.- 2009.- 38(5).- Р 1297-309.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Glei D.A., Goldman N., Chuang Y.-L., Weinstein M. Do chronic stressors lead to physiological dysregulation? Testing the theory of allostatic load // Psychosomatic Med.- 2007.- 69.- Р. 769-776.</mixed-citation><mixed-citation xml:lang="en">Glei D.A., Goldman N., Chuang Y.-L., Weinstein M. Do chronic stressors lead to physiological dysregulation? Testing the theory of allostatic load // Psychosomatic Med.- 2007.- 69.- Р. 769-776.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Juster R-P., McEwen B.S., Lupien S.J. Allostatic load biomarkers of chronic stress and impact on health and cognition //. Neuroscience and Biobehavioral Reviews.- 2010.- 35:2</mixed-citation><mixed-citation xml:lang="en">Juster R-P., McEwen B.S., Lupien S.J. Allostatic load biomarkers of chronic stress and impact on health and cognition //. Neuroscience and Biobehavioral Reviews.- 2010.- 35:2</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Karlamangla A.S., Singer B.H., Seeman T.E. Reduction in allostatic load in older adults is associated with lower all - cause mortality risk: MacArthur studies of successful aging // Psychosom Med.- 2006.- 68(3).- Р. 500-507.</mixed-citation><mixed-citation xml:lang="en">Karlamangla A.S., Singer B.H., Seeman T.E. Reduction in allostatic load in older adults is associated with lower all - cause mortality risk: MacArthur studies of successful aging // Psychosom Med.- 2006.- 68(3).- Р. 500-507.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Mauss D., Li J., Schmidt B., Angerer P., Jarczok M.N. Measuring allostatic load in the workforce: a systematic review // Industrial Health.- 2015.- 53.- 5-20. https://www. jniosh.go.jp/en/ indu_hel/2015.html.</mixed-citation><mixed-citation xml:lang="en">Mauss D., Li J., Schmidt B., Angerer P., Jarczok M.N. Measuring allostatic load in the workforce: a systematic review // Industrial Health.- 2015.- 53.- 5-20. https://www. jniosh.go.jp/en/ indu_hel/2015.html.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">McEwen B.S., Seeman T. Protective and damaging effects of mediators of stress. Elaborating and testing the concepts of allostasis and allostatic load // Annals of the New York Academy of Sciences.- 1999.- 896.- Р. 30-47.</mixed-citation><mixed-citation xml:lang="en">McEwen B.S., Seeman T. Protective and damaging effects of mediators of stress. Elaborating and testing the concepts of allostasis and allostatic load // Annals of the New York Academy of Sciences.- 1999.- 896.- Р. 30-47.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Pencina MJ, D'Agostino RB Sr, DAgostino RB et al. Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond // Stat Med.- 2008.- 27(2).- Р. 157-172.</mixed-citation><mixed-citation xml:lang="en">Pencina MJ, D'Agostino RB Sr, DAgostino RB et al. Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond // Stat Med.- 2008.- 27(2).- Р. 157-172.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Schnorpfeila P., Nolla A., Schulzeb R., Ehlertc U., Freya K., Fischera J.E. Allostatic load and work conditions // Social Science &amp; Medicine.- 2003.- 57.- Р. 647-656.</mixed-citation><mixed-citation xml:lang="en">Schnorpfeila P., Nolla A., Schulzeb R., Ehlertc U., Freya K., Fischera J.E. Allostatic load and work conditions // Social Science &amp; Medicine.- 2003.- 57.- Р. 647-656.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Sterling P. Allostasis: A model of predictive regulation // Physiology &amp; Behavior.- 2012.- 106.- Р. 5-15.</mixed-citation><mixed-citation xml:lang="en">Sterling P. Allostasis: A model of predictive regulation // Physiology &amp; Behavior.- 2012.- 106.- Р. 5-15.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
