zurniimtpeМедицина труда и промышленная экологияRussian Journal of Occupational Health and Industrial Ecology1026-94282618-8945FSBSI “Izmerov Research Institute of Occupational Health”10.31089/1026-9428-2025-65-11-735-740btuifpzurniimtpe-3990Research ArticleОБЗОРЫ ЛИТЕРАТУРЫLITERATURE REVIEWSЛокальная инъекционная терапия при вибрационной болезни: современные подходы и перспективыLocal injection therapy for vibration disease: modern approaches and prospectshttps://orcid.org/0009-0003-5316-2548ЗуеваЯнина ИозавнаZuevaYanina I.

Врач-ревматолог, ФГБНУ «Восточно-Сибирский институт медико-экологических исследований».

e-mail: mabtera83@gmail.com

Rheumatologist (Clinic), East-Siberian Institute of Medical and Ecological Research.

e-mail: mabtera83@gmail.com

mabtera83@gmail.comФГБНУ «Восточно-Сибирский институт медико-экологических исследований»РоссияEast-Siberian Institute of Medical and Ecological ResearchRussian Federation2025101220256511735740Copyright © Зуева Я.И., 20252025Зуева Я.И.Zueva Y.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.journal-irioh.ru/jour/article/view/3990

В данном обзоре анализируется эффективность различных методов локальной инъекционной терапии при вибрационной болезни, учитывая многообразие её клинических проявлений. Анализ существующих исследований показывает противоречивые результаты применения глюкокортикоидов, ограниченную доказательную базу для гиалуроновой кислоты, а также обнадёживающие, но требующие дальнейшего изучения данные по эффективности раствора декстрозы, препаратов плазмы и ботулинотоксина.

Обзор подчёркивает необходимость проведения более масштабных и контролируемых исследований для установления оптимальной стратегии локальной инъекционной терапии при вибрационной болезни, с учётом хронического характера заболевания и потенциальных побочных эффектов некоторых препаратов.

Перспективными направлениями исследований являются изучение механизмов действия и сравнительная эффективность указанных препаратов при различных проявлениях вибрационной болезни, включая тендинопатии, туннельные синдромы и вазоспастические нарушения.

Этика

Этика. На проведение экспериментов было получено разрешение Локального этического комитета ФГБНУ ВСИМЭИ (протокол № 2 от 17.03.2025).

Финансирование

Финансирование. Работа выполнена в рамках средств, выделяемых для выполнения государственного задания ФГБНУ ВСИМЭИ.

Конфликт интересов

Конфликт интересов. Автор заявляет об отсутствии конфликта интересов.

Дата поступления

Дата поступления: 16.06.2025 / Дата принятия к печати: 06.11.2025 / Дата публикации: 10.12.2025

This review analyzes the effectiveness of various methods of local injection therapy for vibration disease (VD), taking into account the variety of its clinical manifestations.

An analysis of existing studies shows contradictory results of the use of glucocorticoids, a limited evidence base for hyaluronic acid, as well as encouraging, but requiring further study, data on the effectiveness of dextrose solution, plasma preparations and botulinum toxin. The review highlights the need for larger-scale and controlled studies to establish an optimal strategy for local injection therapy in VD, taking into account the chronic nature of the disease and the potential side effects of certain drugs. Promising areas of research are the study of the mechanisms of action and the comparative effectiveness of these drugs in various manifestations of VD, including tendinopathy, tunnel syndromes and vasospastic disorders.

Ethics

Ethics. The experiments were approved by the Local Ethics Committee of the East-Siberian Institute of Medical and Ecological Research (Protocol No. 2 dated 03/17/2025).

Funding

Funding. The work was carried out within the Framework of funds allocated to fulfill the state assignment of the East-Siberian Institute of Medical and Ecological Research.

Conflict of interest

Conflict of interest. The author declares no conflict of interest.

Received

Received: 16.06.2025 / Accepted: 06.11.2025 / Published: 10.12.2025

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The authors declare that there are no conflicts of interest present.