zurniimtpeМедицина труда и промышленная экологияRussian Journal of Occupational Health and Industrial Ecology1026-94282618-8945FSBSI “Izmerov Research Institute of Occupational Health”10.31089/1026-9428-2025-65-10-660-671wdgobkzurniimtpe-3970Research ArticleОБЗОРЫ ЛИТЕРАТУРЫLITERATURE REVIEWSРепродуктивное здоровье женщин работников при действии вредных производственных факторов: современное состояние проблемыReproductive health of female workers under the influence of harmful industrial factors: the current state of the problemhttps://orcid.org/0000-0001-7136-1442ФесенкоМарина АлександровнаFesenkoMarina A.

Зав. лаб. профилактики нарушений репродуктивного здоровья работников ФГБНУ «НИИ МТ», д-р мед. наук.

e-mail: fesenkoma@irioh.ru

Head of the Laboratory for the Prevention of Reproductive Health Disorders in Workers, Izmerov Research Institute of Occupational Health, Dr. of Sci. (Med.).

e-mail: fesenkoma@irioh.ru

fesenkoma@irioh.ruhttps://orcid.org/0000-0002-6693-4186ГолованеваГалина ВладимировнаGolovanevaGalina V.

Ведущий научный сотрудник лаборатории профилактики нарушений репродуктивного здоровья работников ФГБНУ «НИИ МТ», д-р мед. наук.

e-mail: galstella@mail.ru

Leading Researcher, Laboratory for the Prevention of Reproductive Health Disorders in Workers, Izmerov Research Institute of Occupational Health, Dr. of Sci. (Med.).

e-mail: galstella@mail.ru

galstella@mail.ruhttps://orcid.org/0000-0001-9340-2284ГайнуллинаМахмуза КалимовнаGainullinaMakhmuza K.

Вед. науч. сотр. отдела медицины труда ФБУН «Уфимский НИИ медицины труда и экологии человека» Российская Федерация, Республика Башкортостан, д-р мед. наук, профессор

e-mail: gainullinamk@mail.ru

Leading Researcher, Department of Occupational Medicine, Ufa Research Institute of Occupational Medicine and Human Ecology, Dr. of Sci. (Med.), Professor.

e-mail: gainullinamk@mail.ru

gainullinamk@mail.ruhttps://orcid.org/0000-0002-2007-4731МителеваТатьяна ЮрьевнаMitelevaTatyana Yu.

Ст. науч. сотр. лаб. профилактики нарушений репродуктивного здоровья работников ФГБНУ «НИИ МТ», канд. мед. наук.

e-mail: miteleva@irioh.ru

Senior Researcher, Laboratory for the Prevention of Reproductive Health Disorders in Workers, Izmerov Research Institute of Occupational Health, Cand. of Sci. (Med.).

e-mail: miteleva@irioh.ru

miteleva@irioh.ruhttps://orcid.org/0000-0003-4824-4648ВуйцикПетр АлександровичVuytsikPetr A.

Науч. сотр. лаб. профилактики нарушений репродуктивного здоровья работников ФГБНУ «НИИ МТ».

e-mail: pv1985@mail.ru

Researcher, Laboratory for the Prevention of Reproductive Health Disorders in Workers, Izmerov Research Institute of Occupational Health.

e-mail: pv1985@mail.ru

pv1985@mail.ruУткинаНаталья СергеевнаUtkinaNatalya S.

Врач акушер-гинеколог, клиника профессиональных и производственно обусловленных заболеваний, ФГБНУ «НИИ МТ»

e-mail: tasha_2205@mail.ru

Obstetrician-Gynecologist, Clinic of Occupational and Work-Related Diseases, Izmerov Research Institute of Occupational Health.

e-mail: tasha_2205@mail.ru

tasha_2205@mail.ruФГБНУ «Научно-исследовательский институт медицины труда имени академика Н.Ф. Измерова»РоссияIzmerov Research Institute of Occupational HealthRussian FederationФБУН «Уфимский научно-исследовательский институт медицины труда и экологии человека»РоссияUfa Research Institute of Occupational Health and Human EcologyRussian FederationФГБНУ «Научно-исследовательский институт медицины труда имени академика Н.Ф. Измерова»; ФГАОУ ВО Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет)РоссияIzmerov Research Institute of Occupational Health; I.M. Sechenov First Moscow State Medical University (Sechenov University)Russian Federation2025211120256510660671Copyright © Фесенко М.А., Голованева Г.В., Гайнуллина М.К., Мителева Т.Ю., Вуйцик П.А., Уткина Н.С., 20252025Фесенко М.А., Голованева Г.В., Гайнуллина М.К., Мителева Т.Ю., Вуйцик П.А., Уткина Н.С.Fesenko M.A., Golovaneva G.V., Gainullina M.K., Miteleva T.Y., Vuytsik P.A., Utkina N.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.journal-irioh.ru/jour/article/view/3970

Сохранение репродуктивного здоровья женщин работниц — приоритетная задача медицины труда и демографической политики. Проанализированы современные (2000–2025 гг.) рецензируемые публикации из международных (PubMed, MEDLINE, Scopus) и российских (eLibrary, РИНЦ) научных баз данных, посвящённые влиянию профессиональных рисков на репродуктивное здоровье работниц. С применением строгих критериев включения/исключения были отобраны оригинальные исследования, систематические обзоры и мета-анализы, содержащие количественные оценки риска. Для анализа использовались стандартизированные эпидемиологические показатели: отношение шансов (OR), относительный риск (RR) и этиологическая доля (EF). Результаты обзора демонстрируют статистически значимую связь между воздействием вредных производственных факторов и нарушениями репродуктивной функции, включая осложнения беременности и снижение фертильности.

Представленный анализ убедительно показывает, что проблема охраны репродуктивного здоровья работников (особенно женщин) имеет социальное и демографическое значение и подчёркивает необходимость перехода от простого выявления уже существующих нарушений к оценке и управлению профессиональными рисками.

Участие авторов

Участие авторов:Фесенко М.А. — концепция и дизайн исследования, анализ и интерпретация данных; одобрение окончательной версии;Голованева Г.В. — концепция и дизайн исследования, анализ и интерпретация данных, редактирование;Гайнуллина М.К. — концепция и дизайн исследования, анализ и интерпретация данных, редактирование;Мителева Т.Ю. — сбор и обработка материала, написание текста;Вуйцик П.А. — сбор материала, написание текста раздела статьи;Уткина Н.С. — сбор материала, написание текста раздела статьи;Все авторы — утверждение окончательного варианта статьи, ответственность за целостность всех частей статьи.

Финансирование

Финансирование. Исследование не имело спонсорской поддержки.

Конфликт интересов

Конфликт интересов. Авторы статьи сообщают об отсутствии конфликта интересов.

Дата поступления

Дата поступления: 06.10.2025 / Дата принятия к печати: 20.10.2025 / Дата публикации: 21.11.2025

Preserving the reproductive health of female workers is a priority task of occupational health and demographic policy. Modern (2000–2025) peer-reviewed publications from international (PubMed, MEDLINE, Scopus) and Russian (eLibrary, RSCI) scientific databases on the impact of occupational risks on the reproductive health of female workers are analyzed.

The authors selected original studies, systematic reviews, and meta-analyses containing quantitative risk assessments using strict inclusion/exclusion criteria. For the analysis, they used standardized epidemiological indicators: odds ratio (OR), relative risk (RR) and etiological proportion (EF). The review results demonstrate a statistically significant association between exposure to harmful occupational factors and reproductive function disorders, including pregnancy complications and decreased fertility.

The presented analysis convincingly shows that the problem of protecting the reproductive health of workers (especially women) is of social and demographic importance and emphasizes the need to move from simply identifying existing disorders to assessing and managing occupational risks.

Contributions

Contributions:Fesenko M.A. — research concept and design, data analysis and interpretation; approval of the final version;Golovaneva G.V. — research concept and design, data analysis and interpretation, editing;Gainullina M.K. — research concept and design, data analysis and interpretation, editing;Miteleva T.Y. — collecting and processing material, writing text;Vujtsik P.A. — collecting material, writing the text of the article section;Utkina N.S. — collecting material, writing the text of the article section;All authors — approving the final version of the article and for ensuring the integrity of all parts of the article.

Funding

Funding. The study had no funding.

Conflict of interest

Conflict of interest. The authors declare no conflict of interest.

Received

Received: 06.10.2025 / Accepted: 20.10.2025 / Published: 21.11.2025

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The authors declare that there are no conflicts of interest present.