zurniimtpeМедицина труда и промышленная экологияRussian Journal of Occupational Health and Industrial Ecology1026-94282618-8945FSBSI “Izmerov Research Institute of Occupational Health”10.31089/1026-9428-2023-63-12-835-840xgnbcnzurniimtpe-3356Research ArticleПРАКТИЧЕСКОМУ ЗДРАВООХРАНЕНИЮFOR THE PRACTICAL MEDICINEПрофессиональные злокачественные новообразования почек и мочевых путейOccupational malignant neoplasms of the kidney and urinary tracthttps://orcid.org/0000-0003-0654-1046АрхиповЕвгений В.ArkhipovEvgenii V.noemail@neicon.ruhttps://orcid.org/0000-0001-8986-8030ГариповаРаиля В.GaripovaRailya V.noemail@neicon.ruhttps://orcid.org/0000-0002-2291-6453СтрижаковЛеонид АлександровичStrizhakovLeonid A.

Профессор кафедры внутренних, профессиональных болезней и ревматологии ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России, руководитель Центра профессиональной патологии Минздрава России, д-р мед. наук

e-mail: strizhakov76@mail.ru

Professor of the Department of Internal, Occupational Diseases and Rheumatology at I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, the Head of the Center for Occupational Pathology of the Ministry of Health, Russian Federation, Dr. of Sci. (Med.)

e-mail: strizhakov76@mail.ru

strizhakov76@mail.ruФГБОУ ВО «Казанский государственный медицинский университет» Минздрава РоссииРоссияKazan State Medical UniversityRussian FederationФГБОУ ВО «Казанский государственный медицинский университет» Минздрава России; Институт фундаментальной медицины и биологии ФГАОУ ВО «Казанский (Приволжский) федеральный университет»; Казанская государственная медицинская академия — филиал ФГБОУ ДОП «Российская медицинская академия непрерывного профессионального образования» Минздрава РоссииРоссияKazan State Medical University; Institute of Fundamental Medicine and Biology; Kazan State Medical Academy, Branch of the Russian Medical Academy of Continuing Professional Education of the Ministry of Health of RussiaRussian FederationSechenov First Moscow State Medical UniversityRussian Federation2023090120246312835840Copyright © Архипов Е.В., Гарипова Р.В., Стрижаков Л.А., 20242024Архипов Е.В., Гарипова Р.В., Стрижаков Л.А.Arkhipov E.V., Garipova R.V., Strizhakov L.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.journal-irioh.ru/jour/article/view/3356

Эпидемиологическая характеристика многих профессиональных поражений органов мочевыводящей системы остаётся малоизученной и неуточнённой, так как их описывают только в виде спорадических отдельных или групповых случаев.

Заболевания, возникающие от воздействия промышленных канцерогенов, остаются актуальной проблемой медицины труда. К сожалению, на сегодняшний день отмечается низкая выявляемость профессиональных злокачественных новообразований любой локализации. Профессиональные онкологические заболевания с поражением почек и мочевых путей развиваются вследствие прямого контакта с производственным фактором, обладающим канцерогенным действием.

Выполнен анализ проведённых исследований, посвящённых проблеме профессиональных онкологических поражений почек и мочевых путей, частота которых остаётся недооценённой в связи с их скрытым клиническим течением и влиянием факторов внешней среды, что требует дальнейшего изучения данного вопроса.

Для своевременной диагностики злокачественных новообразований органов мочевыводящей системы после достижения стажа в пять лет рекомендовано проведение ультразвукового исследования почек и мочевыводящих путей и цистоскопию с периодичностью один раз в пять лет в центре профессиональной патологии лицам, работающим в условиях контакта с канцерогенами.

Участие авторов

Участие авторов:

Архипов Е

Архипов Е.В. — концепция и дизайн исследования, написание текста;

Гарипова Р

Гарипова Р.В. — написание текста;

Стрижаков Л

Стрижаков Л.А. — редактирование.

Финансирование

Финансирование. Исследование не имело спонсорской поддержки.

Конфликт интересов

Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.

Дата поступления

Дата поступления: 27.11.2023 / Дата принятия к печати: 05.12.2023 / Дата публикации: 29.12.2023

The epidemiological characteristics of many occupational lesions of the urinary tract organs remain poorly understood and unspecified, since they are described only as sporadic individual or group cases.

Diseases arising from exposure to industrial carcinogens remain an urgent problem in occupational health. Unfortunately, today there is a low detection rate of occupational malignancies of any localization. Occupational oncological diseases with damage to the kidneys and urinary tract develop as a result of direct contact with a production factor with a carcinogenic effect.

The analysis of the conducted studies devoted to the problem of occupational oncological lesions of the kidneys and urinary tract, the frequency of which remains underestimated due to their latent clinical course and the influence of environmental factors, which requires further study of this issue.

For timely diagnosis of malignant neoplasms of the urinary system organs after reaching the length of service of five years, it is recommended to conduct an ultrasound examination of the kidneys and urinary tract and cystoscopy once every five years at the center of occupational pathology for persons working in contact with carcinogens.

Contribution

Contribution:Arkhipov E.V. — the concept and design of the study, writing the text;Garipova R.V. — writing the text;Strizhakov L.A. — the editing.

Funding

Funding. The study had no funding.

Conflict of interests

Conflict of interests. The authors declare no conflict of interests.

Received

Received: 27.11.2023 / Accepted: 05.12.2023 / Published: 29.12.2023

профессиональные злокачественные новообразованияпочкимочевой пузырьпериодические медицинские осмотрыoccupational malignancieskidneysbladderperiodic medical examinationsReferencesЗлокачественные новообразования в России в 2021 году (заболеваемость и смертность). Под ред. А.Д. Каприна, В.В. Старинского, А.О. Шахзадовой. М.: МНИОИ им. П.А. Герцена — филиал ФГБУ «НМИЦ радиологии» Минздрава России; 2022.Kaprin A.D., Starinsky V.V., Shakhzadova A.O. Malignant neoplasms in Russia in 2021 (morbidity and mortality). M.: MNIOI im. P.A. Gercena — filial FGBU «NMIC radiologii» Minzdrava Rossii; 2022 (in Russian).GBD 2016 Occupational Carcinogens Collaborators. Global and regional burden of cancer in 2016 arising from occupational exposure to selected carcinogens: a systematic analysis for the Global Burden of Disease Study 2016. Occup. Environ. Med. 2020; 77(3): 151–159. https://doi.org/10.1136/oemed-2019-106012GBD 2016 Occupational Carcinogens Collaborators. Global and regional burden of cancer in 2016 arising from occupational exposure to selected carcinogens: a systematic analysis for the Global Burden of Disease Study 2016. Occup. Environ. Med. 2020; 77(3): 151–159. https://doi.org/10.1136/oemed-2019-106012GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020; 396(10258): 1204–1222. https://doi.org/10.1016/S0140-6736(20)30925-9GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020; 396(10258): 1204–1222. https://doi.org/10.1016/S0140-6736(20)30925-9Siegel R.L., Miller K.D., Jemal A. Cancer statistics, 2016. CA Cancer J. Clin. 2016; 66(1): 7–30. https://doi.org/10.3322/caac.21332Siegel R.L., Miller K.D., Jemal A. Cancer statistics, 2016. CA Cancer J Clin. 2016; 66(1): 7–30. https://doi.org/10.3322/caac.21332Chow W.H., Dong L.M., Devesa S.S. Epidemiology and risk factors for kidney cancer. Nat Rev Urol. 2010; 7(5): 245–257. https://doi.org/10.1038/nrurol.2010.46Chow W.H., Dong L.M., Devesa S.S. Epidemiology and risk factors for kidney cancer. Nat Rev Urol. 2010; 7(5): 245–257. https://doi.org/10.1038/nrurol.2010.46Гарипова Р.В., Стрижаков Л.А., Архипов Е.В. Профессиональные поражения почек от воздействия физических и биологических факторов. Мед. труда и пром. экол. 2019; 1: 38–44. https://doi.org/10.31089/1026-9428-2019-1-38-44Garipova R.V., Strizhakov L.A., Arkhipov E.V. Occupational kidney disorders from physical and biologic factors. Med. truda i prom. ekol. 2019; 1: 38–44. https://doi.org/10.31089/1026–9428–2019–1–38–44 (in Russian).GBD 2016 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 84 behavioral, environmental and occupational, and metabolic risks or clusters of risks, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017; 390(10100): 1345–1422. https://doi.org/10.1016/S0140-6736(17)32366-8GBD 2016 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 84 behavioral, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017; 390(10100): 1345–1422. https://doi.org/10.1016/S0140-6736(17)32366-87Серебряков П.В. Профессиональный рак. Проблемы выявляемости. Мед. труда и пром. экол. 2019; 59(9): 749–750. https://doi.org/10.31089/1026-9428-2019-59-9-749-750Serebryakov P.V. Occupational cancer. The problem of the detection. Med. truda i prom ekol. 2019; 59(9). https://doi.org/10.31089/1026-9428-2019-59-9-749-750 (in Russian).О состоянии санитарно-эпидемиологического благополучия населения в Российской Федерации в 2019 году: Государственный доклад. М.: Федеральная служба по надзору в сфере защиты прав потребителей и благополучия человека; 2020. https://clck.ru/377ABBOn the state of sanitary and epidemiological well-being of the population in the Russian Federation in 2019: State report. M.: Federal Service for Supervision of Consumer Rights Protection and human well-being, 2020. https://clck.ru/377ABB (in Russian).Paganini-Hill A., Glazer E., Henderson B.E., Ross R.K. Cause-specific mortality among newspaper web pressmen. J. Occup. Med. 1980; 22(8): 542–544. https://doi.org/10.1097/00043764-198008000-00011Paganini-Hill A., Glazer E., Henderson B.E., Ross R.K. Cause-specific mortality among newspaper web pressmen. J. Occup. Med. 1980; 22(8): 542–544. https://doi.org/10.1097/00043764-198008000-00011McLaughlin J.K., Blot W.J., Mehl E.S., Stewart P.A., Venable F.S., Fraumeni J.F. Jr. Petroleum-related employment and renal cell cancer. J. Occup. Med. 1985; 27(9): 672–674.McLaughlin J.K., Blot W.J., Mehl E.S., Stewart P.A., Venable F.S., Fraumeni J.F.Jr. Petroleum-related employment and renal cell cancer. J. Occup. Med. 1985; 27(9): 672–674.Enterline P.E., Hartley J., Henderson V. Asbestos and cancer: a cohort followed up to death. Br J Ind Med. 1987; 44(6): 396–401 https://doi.org/10.1136/oem.44.6.396Enterline P.E., Hartley J., Henderson V. Asbestos and cancer: a cohort followed up to death. Br J Ind Med. 1987; 44(6): 396–401. https://doi.org/10.1136/oem.44.6.396Brownson R.C. A case-control study of renal cell carcinoma in relation to occupation, smoking, and alcohol consumption. Arch Environ Health. 1988; 43(3): 238–241. https://doi.org/10.1080/00039896.1988.9934940Brownson R.C. A case-control study of renal cell carcinoma in relation to occupation, smoking, and alcohol consumption. Arch. Environ. Health. 1988; 43(3): 238–241. https://doi.org/10.1080/00039896.1988.9934940Kadamani S., Asal N.R., Nelson R.Y. Occupational hydrocarbon exposure and risk of renal cell carcinoma. Am. J. Ind. Med. 1989; 15(2): 131–141. https://doi.org/10.1002/ajim.4700150202Kadamani S., Asal N.R., Nelson R.Y. Occupational hydrocarbon exposure and risk of renal cell carcinoma. Am. J. Ind. Med. 1989; 15(2): 131–141. https://doi.org/10.1002/ajim.4700150202Asal N.R., Geyer J.R., Risser D.R., Lee E.T., Kadamani S., Cherng N. Risk factors in renal cell carcinoma. II. Medical history, occupation, multivariate analysis, and conclusions. Cancer Detect Prev. 1988; 13(3–4): 263–279.Asal N.R., Geyer J.R., Risser D.R., Lee E.T., Kadamani S., Cherng N. Risk factors in renal cell carcinoma. II. Medical history, occupation, multivariate analysis, and conclusions. Cancer Detect Prev. 1988; 13(3–4): 263–279.Siemiatycki J., Gérin M., Stewart P., Nadon L., Dewar R., Richardson L. Associations between several sites of cancer and ten types of exhaust and combustion products. Results from a case-referent study in Montreal. Scand J Work Environ Health. 1988; 14(2): 79–90. https://doi.org/10.5271/sjweh.1949Siemiatycki J., Gérin M., Stewart P., Nadon L., Dewar R., Richardson L. Associations between several sites of cancer and ten types of exhaust and combustion products. Results from a case-referent study in Montreal. Scand J Work Environ Health. 1988; 14(2): 79–90. https://doi.org/10.5271/sjweh.1949Kolonel L.N. Association of cadmium with renal cancer. Cancer. 1976; 37(4): 1782–1787. https://clck.ru/37Ky4NKolonel L.N. Association of cadmium with renal cancer. Cancer. 1976; 37(4): 1782-1787. https://clck.ru/37Ky4NSelevan S.G., Landrigan P.J., Stern F.B., Jones J.H. Mortality of lead smelter workers. Am J Epidemiol. 1985; 122(4): 673–683. https://doi.org/10.1093/oxfordjournals.aje.a114146Selevan S.G., Landrigan P.J., Stern F.B., Jones J.H. Mortality of lead smelter workers. Am J Epidemiol. 1985; 122(4): 673–683. https://doi.org/10.1093/oxfordjournals.aje.a114146Maclure M. Asbestos and renal adenocarcinoma: a case-control study. Environ Res. 1987; 42(2): 353–361. https://doi.org/10.1016/s0013-9351(87)80200-1Maclure M. Asbestos and renal adenocarcinoma: a case-control study. Environ. Res. 1987; 42(2): 353–361. https://doi.org/10.1016/s0013-9351(87)80200-1Capitanio U., Montorsi F. Renal cancer. Lancet. 2016; 387(10021): 894–906. https://doi.org/10.1016/S0140-6736(15)00046-XCapitanio U., Montorsi F. Renal cancer. Lancet. 2016; 387(10021): 894–906. https://doi.org/10.1016/S0140-6736(15)00046-XSung H., Ferlay J., Siegel R.L., Laversanne M., Soerjomataram I., Jemal A., Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J. Clin. 2021; 71(3): 209–249. https://doi.org/ 10.3322/caac.21660Sung H., Ferlay J., Siegel R.L., Laversanne M., Soerjomataram I., Jemal A., Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021; 71(3): 209–249. https://doi.org/10.3322/caac.21660Mandel J.S., McLaughlin J.K., Schlehofer B., Mellemgaard A., Helmert U., Lindblad P., McCredie M., Adami H.O. International renal-cell cancer study. IV. Occupation. Int J Cancer. 1995; 61(5): 601–605. https://doi.org/10.1002/ijc.2910610503Mandel J.S., McLaughlin J.K., Schlehofer B., Mellemgaard A., Helmert U., Lindblad P., McCredie M., Adami H.O. International renal-cell cancer study. IV. Occupation. Int. J. Cancer. 1995; 61(5): 601–605. https://doi.org/10.1002/ijc.2910610503Kelsh M.A., Alexander D.D., Mink P.J., Mandel J.H. Occupational trichloroethylene exposure and kidney cancer: a meta-analysis. Epidemiology. 2010; 21(1): 95–102. https://doi.org/10.1097/EDE.0b013e3181c30e92Kelsh M.A., Alexander D.D., Mink P.J., Mandel J.H. Occupational trichloroethylene exposure and kidney cancer: a meta-analysis. Epidemiology. 2010; 21(1): 95–102. https://doi.org/10.1097/EDE.0b013e3181c30e92Brüning T., Pesch B., Wiesenhütter B., Rabstein S., Lammert M., Baumüller A., Bolt H.M. Renal cell cancer risk and occupational exposure to trichloroethylene: results of a consecutive case-control study in Arnsberg, Germany. Am. J. Ind. Med. 2003; 43(3): 274–285. https://doi.org/10.1002/ajim.10185Brüning T., Pesch B., Wiesenhütter B., Rabstein S., Lammert M., Baumüller A., Bolt H.M. Renal cell cancer risk and occupational exposure to trichloroethylene: results of a consecutive case-control study in Arnsberg, Germany. Am. J. Ind. Med. 2003; 43(3): 274–285. https://doi.org/10.1002/ajim.10185Charbotel B., Fevotte J., Hours M., Martin J.L., Bergeret A. Case-control study on renal cell cancer and occupational exposure to trichloroethylene. Part II: Epidemiological aspects. Ann. Occup. Hyg. 2006; 50(8): 777–787. https://doi.org/10.1093/annhyg/mel039Charbotel B., Fevotte J., Hours M., Martin J.L., Bergeret A. Case-control study on renal cell cancer and occupational exposure to trichloroethylene. Part II: Epidemiological aspects. Ann. Occup. Hyg. 2006; 50(8): 777–787. https://doi.org/10.1093/annhyg/mel039Scott C.S., Jinot J. Trichloroethylene and cancer: systematic and quantitative review of epidemiologic evidence for identifying hazards. Int. J. Environ. Res. Public Health. 2011; 8(11): 4238–4272. https://doi.org/10.3390/ijerph8114238Scott C.S., Jinot J. Trichloroethylene and cancer: systematic and quantitative review of epidemiologic evidence for identifying hazards. Int. J. Environ. Res. Public Health. 2011; 8(11): 4238–4272. https://doi.org/10.3390/ijerph8114238Karami S., Lan Q., Rothman N., Stewart P.A., Lee K.M., Vermeulen R., Moore L.E. Occupational trichloroethylene exposure and kidney cancer risk: a meta-analysis. Occup. Environ. Med. 2012; 69(12): 858–867. https://doi.org/10.1136/oemed-2012-100932Karami S., Lan Q., Rothman N., Stewart P.A., Lee K.M., Vermeulen R., Moore L.E. Occupational trichloroethylene exposure and kidney cancer risk: a meta-analysis. Occup. Environ. Med. 2012; 69(12): 858–867. https://doi.org/10.1136/oemed-2012-100932Темкин И.С. Опухоли мочевого пузыря, вызванные канцерогенными аминосоединениями. М.: Медгиз, 1957.Temkin I.S. Bladder tumors caused by carcinogenic aminocompounds. M.: Medgiz; 1957 (in Russian).Boyland E. The biochemistry of cancer of the bladder. Br. Med. Bull. 1958; 14(2): 153–158. https://doi.org/10.1093/oxfordjournals.bmb.a069659Boyland E. The biochemistry of cancer of the bladder. Br. Med. Bull. 1958; 14(2): 153–158. https://doi.org/10.1093/oxfordjournals.bmb.a069659Vineis P., Segnan N., Costa G., Terracini B. Evidence of a multiplicative effect between cigarette smoking and occupational exposures in the aetiology of bladder cancer. Cancer. Lett. 1981; 14(3): 285–290. https://doi.org/ 10.1016/0304-3835(81)90156-7Vineis P., Segnan N., Costa G., Terracini B. Evidence of a multiplicative effect between cigarette smoking and occupational exposures in the aetiology of bladder cancer. Cancer. Lett. 1981; 14(3): 285–290. https://doi.org/ 10.1016/0304-3835(81)90156-7Пряничникова М.Б. Современные гипотезы возникновения рака мочевого пузыря. Урология. 2014; 1: 88–89.Pryanichnikova M.B. Modern hypotheses of the origin of bladder cancer. Urologiy. 2014; 1: 88–89 (in Russian).Johnson E.S., Fischman H.R. Cancer mortality among butchers and slaughterhouse workers. Lancet. 1982; 1(8277): 913–914. https://doi.org/10.1016/s0140-6736(82)92186-9Johnson E.S., Fischman H.R. Cancer mortality among butchers and slaughterhouse workers. Lancet. 1982; 1(8277): 913–914. https://doi.org/10.1016/s0140-6736(82)92186-9Silverman D.T., Devesa S.S., Moore L.E., Rothman N. Bladder Cancer. Schottenfeld D., Fraumeni J.F., eds. Cancer Epidemiology and Prevention. 2006: 1101–1127. https://clck.ru/37KyTkSilverman D.T., Devesa S.S., Moore L.E., Rothman N. Bladder Cancer. Schottenfeld D., Fraumeni J.F., eds. Cancer Epidemiology and Prevention. 2006: 1101–1127. https://clck.ru/37KyTk

The authors declare that there are no conflicts of interest present.