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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zurniimtpe</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина труда и промышленная экология</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Occupational Health and Industrial Ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1026-9428</issn><issn pub-type="epub">2618-8945</issn><publisher><publisher-name>FSBSI “Izmerov Research Institute of Occupational Health”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31089/1026-9428-2023-63-6-386-396</article-id><article-id custom-type="edn" pub-id-type="custom">wpynoy</article-id><article-id custom-type="elpub" pub-id-type="custom">zurniimtpe-3201</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEW</subject></subj-group></article-categories><title-group><article-title>Кремнезём: профессиональные риски нарушений здоровья</article-title><trans-title-group xml:lang="en"><trans-title>Silica: occupational risks of health disorders</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9107-7964</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горблянский</surname><given-names>Юрий Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorblyansky</surname><given-names>Yuri Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8531-5703</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шуякова</surname><given-names>Екатерина А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shuyakova</surname><given-names>Ekaterina A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0050-5645</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Конторович</surname><given-names>Елена Павловна</given-names></name><name name-style="western" xml:lang="en"><surname>Kontorovich</surname><given-names>Elena P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доцент кафедры профпатологии, ФГБОУ ВО «Ростовский государственный медицинский университет» МЗ РФ, Ростов-на-Дону, канд. мед. наук.</p><p>e-mail: kontorovichep@yandex.ru </p></bio><bio xml:lang="en"><p>Associate Professor of the Department of Occupational Pathology, Rostov State Medical University, Ministry of Health of Russian Federation, Rostov-on-Don, Cand. of Sci. (Med.).</p><p>e-mail: kontorovichep@yandex.ru</p></bio><email xlink:type="simple">kontorovichep@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0149-1281</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Понамарева</surname><given-names>Оксана П.</given-names></name><name name-style="western" xml:lang="en"><surname>Ponamareva</surname><given-names>Oksana P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ ВО «Ростовский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rostov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>16</day><month>06</month><year>2023</year></pub-date><volume>63</volume><issue>6</issue><fpage>386</fpage><lpage>396</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Горблянский Ю.Ю., Шуякова Е.А., Конторович Е.П., Понамарева О.П., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Горблянский Ю.Ю., Шуякова Е.А., Конторович Е.П., Понамарева О.П.</copyright-holder><copyright-holder xml:lang="en">Gorblyansky Y.Y., Shuyakova E.A., Kontorovich E.P., Ponamareva O.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.journal-irioh.ru/jour/article/view/3201">https://www.journal-irioh.ru/jour/article/view/3201</self-uri><abstract><p>Представлен анализ современных взглядов на риски производственного воздействия кремнезёма. Описана история изучения проблемы за рубежом и в России. Представлены заболевания, связанные с кремнезёмом, как в традиционных, так и в новых сферах экономики. Рассмотрена связь воздействия диоксида кремния с формированием аутоиммунных заболеваний, хронической обструктивной болезни лёгких, патологии почек, сердечно-сосудистой системы и др. Описаны современные взгляды на механизмы развития лёгочных и внелёгочных заболеваний, связанных с воздействием диоксида кремния. Рассмотрены современные подходы к профилактике мультисистемных рисков, ассоциированных с кремнезёмом.</p><sec><title>Этика</title><p>Этика. Исследование не требовало заключения этического комитета.</p></sec><sec><title>Участие авторов</title><p>Участие авторов:Горблянский Ю.Ю. — концепция и дизайн исследования, написание текста;Шуякова Е.А. — написание текста;Конторович Е.П. — написание текста, редактирование;Понамарева О.П. — написание текста, оформление библиографии.</p></sec><sec><title>Финансирование</title><p>Финансирование. Исследование не имело спонсорской поддержки.</p></sec><sec><title>Конфликт интересов</title><p>Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.</p></sec><sec><title>Дата поступления</title><p>Дата поступления: 08.05.2023 / Дата принятия к печати: 18.05.2023 / Дата публикации: 12.06.2023</p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><p>The authors presented an analysis of modern views on the risks of industrial exposure to silica.</p><p>We touch upon the study of this problem abroad and in Russia. Researchers describe diseases associated with silica, both in traditional and new spheres of the economy.</p><p>In the article, scientists have considered the relationship of exposure to silicon dioxide with the formation of autoimmune, сhronic obstructive pulmonary disease (COPD), kidney pathology, cardiovascular system, etc. The article tells about modern views on the mechanisms of development of pulmonary and extrapulmonary diseases associated with exposure to silicon dioxide. The authors have presented modern approaches to the prevention of multisystem risks associated with silica.</p><sec><title>Ethics</title><p>Ethics. The study did not require the conclusion of the Ethics Committee.</p></sec><sec><title>Contrubution</title><p>Contrubution:Gorblyansky Yu.Yu. — the concept and design of the study, writing the text;Shuyakova E.A. — writing the text;Kontorovich E.P. — writing text, editing;Ponamareva O.P. — writing of the text, design of the bibliography.</p></sec><sec><title>Funding</title><p>Funding. The study had no funding.</p></sec><sec><title>Conflict of interests</title><p>Conflict of interests. The authors declare no conflict of interests.</p></sec><sec><title>Received</title><p>Received: 08.05.2023 / Accepted: 18.05.2023 / Published: 12.06.2023</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>кремнезём</kwd><kwd>диоксид кремния</kwd><kwd>пневмокониоз</kwd><kwd>силикоз</kwd><kwd>профессиональные риски</kwd><kwd>профилактика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>silica</kwd><kwd>silicon dioxide</kwd><kwd>pneumoconiosis</kwd><kwd>silicosis</kwd><kwd>occupational risks</kwd><kwd>prevention</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Castranova V., Vallyathan V. Silicosis and coal workers´ pneumoconiosis. Environ Health Perspect. 2000; 108(Suppl 4): 675–684. https://doi.org/10.1289/ehp.00108s4675</mixed-citation><mixed-citation xml:lang="en">Castranova V., Vallyathan V. Silicosis and coal workers´ pneumoconiosis. 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