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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zurniimtpe</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина труда и промышленная экология</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Occupational Health and Industrial Ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1026-9428</issn><issn pub-type="epub">2618-8945</issn><publisher><publisher-name>FSBSI “Izmerov Research Institute of Occupational Health”</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">zurniimtpe-29</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Физико-химические маркеры развития хронической обструктивной болезни легких у промышленных рабочих</article-title><trans-title-group xml:lang="en"><trans-title>Physical and chemical markers of chronic obstructive lung disease development in industrial workers</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Муравлева</surname><given-names>Лариса Евгеньевна</given-names></name><name name-style="western" xml:lang="en"><surname>Muravlyova</surname><given-names>L. E.</given-names></name></name-alternatives><email xlink:type="simple">lem2403@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Молотов-Лучанский</surname><given-names>Вилен Борисович</given-names></name><name name-style="western" xml:lang="en"><surname>Molotov-Luchanskyi</surname><given-names>V. B.</given-names></name></name-alternatives><email xlink:type="simple">vilen53@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бакирова</surname><given-names>Рысжан Емельевна</given-names></name><name name-style="western" xml:lang="en"><surname>Bakirova</surname><given-names>R. E.</given-names></name></name-alternatives><email xlink:type="simple">bakir15@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клюев</surname><given-names>Дмитрий Анатольевич</given-names></name><name name-style="western" xml:lang="en"><surname>Kliuev</surname><given-names>D. A.</given-names></name></name-alternatives><email xlink:type="simple">mythrandir79@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колесникова</surname><given-names>Евгения Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Kolesnikova</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">kolesnikova.evgeniya@gmail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Демидчик</surname><given-names>Людмила Андреевна</given-names></name><name name-style="western" xml:lang="en"><surname>Demidchik</surname><given-names>L. A.</given-names></name></name-alternatives><email xlink:type="simple">Lusenok@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бейникова</surname><given-names>Ирина Васильевна</given-names></name><name name-style="western" xml:lang="en"><surname>Beinikova</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">irena9898@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Карагандинский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Karaganda State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>01</day><month>03</month><year>2015</year></pub-date><volume>0</volume><issue>3</issue><fpage>12</fpage><lpage>15</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Муравлева Л.Е., Молотов-Лучанский В.Б., Бакирова Р.Е., Клюев Д.А., Колесникова Е.А., Демидчик Л.А., Бейникова И.В., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Муравлева Л.Е., Молотов-Лучанский В.Б., Бакирова Р.Е., Клюев Д.А., Колесникова Е.А., Демидчик Л.А., Бейникова И.В.</copyright-holder><copyright-holder xml:lang="en">Muravlyova L.E., Molotov-Luchanskyi V.B., Bakirova R.E., Kliuev D.A., Kolesnikova E.A., Demidchik L.A., Beinikova I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.journal-irioh.ru/jour/article/view/29">https://www.journal-irioh.ru/jour/article/view/29</self-uri><abstract><p>В работе показано, что у больных хронической обструктивной болезни легких (ХОБЛ) как смешанной, так и бронхитической формами средней степени тяжести обнаружено по 2 типа изменения морфотипов фаций плазмы крови. У больных с различными клиническими формами ХОБЛ тяжелой степени зафиксирован однонаправленный характер изменения морфотипов фаций плазмы крови. У больных с разными клиническими формами ХОБЛ средней степени тяжести один из вариантов морфотипов фаций близок к таковому у больных с более тяжелым клиническим течением. Такие фации можно рассматривать как «переходную форму» от средней к тяжелой степени ХОБЛ. Эти результаты представляют интерес для разработки критерия диагностики степени тяжести ХОБЛ, а также дополнительных критериев диагностики степени тяжести.</p></abstract><trans-abstract xml:lang="en"><p>The article demonstrates that patients with chronic obstructive lung disease (COLD) of both mixed and bronchitis forms with medium severity grade appeared to have 2 types of changes in morphologic types of serum faces. Patients with various clinical forms of severe COLD presented unidirectional change in morphologic types of serum faces. Patients with various forms of moderate COLD had one variant of morphologic types of serum faces was close to that in the patients with more severe clinical course - so that face can be considered as a «transitional form» between moderate and severe COLD. These results are interesting in specifying diagnostic criteria of COLD severity and additional diagnostic criteria of the severity grade.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая обструктивная болезнь легких</kwd><kwd>структурообразующие свойства</kwd><kwd>кровь</kwd><kwd>chronic obstructive lung disease</kwd><kwd>structure formation properties</kwd><kwd>blood</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Муравлева Л.Е., Молотов-Лучанский В.Б., Клюев Д.А. и др. // Лаборатория. - 2013. - № 1. - С. 4-5.</mixed-citation><mixed-citation xml:lang="en">Муравлева Л.Е., Молотов-Лучанский В.Б., Клюев Д.А. и др. // Лаборатория. - 2013. - № 1. - С. 4-5.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Респираторная медицина / под ред. 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