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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zurniimtpe</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина труда и промышленная экология</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Occupational Health and Industrial Ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1026-9428</issn><issn pub-type="epub">2618-8945</issn><publisher><publisher-name>FSBSI “Izmerov Research Institute of Occupational Health”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31089/1026-9428-2019-59-9-690-691</article-id><article-id custom-type="elpub" pub-id-type="custom">zurniimtpe-2302</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Клеточно-молекулярные особенности гиперплазии эндометрия в условиях воздействия производственных токсических факторов</article-title><trans-title-group xml:lang="en"><trans-title>Cellular and molecular features of endometrial hyperplasia under the influence of industrial toxic factors</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маринкин</surname><given-names>И. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Marinkin</surname><given-names>I. O.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лисова</surname><given-names>Евгения Сергеевна</given-names></name><name name-style="western" xml:lang="en"><surname>Lisova</surname><given-names>E. S.</given-names></name></name-alternatives><email xlink:type="simple">ok526nsk@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евченко</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Evchenko</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ НСО «Городская клиническая больница №2»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital No. 2</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2019</year></pub-date><volume>0</volume><issue>9</issue><fpage>690</fpage><lpage>690</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Маринкин И.О., Лисова Е.С., Евченко В.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Маринкин И.О., Лисова Е.С., Евченко В.В.</copyright-holder><copyright-holder xml:lang="en">Marinkin I.O., Lisova E.S., Evchenko V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.journal-irioh.ru/jour/article/view/2302">https://www.journal-irioh.ru/jour/article/view/2302</self-uri><abstract><p>Установлено, что особенностями гиперплазии эндометрия в условиях воздействия репротоксикантов являются взаимосвязи с воспалением и оксидативным стрессом. Экспрессия Ki67 была ассоциирована с 8 гидроксидезоксигуанозином, трансформирующим фактором роста B1сыворотки, воздействием свинца, стажем, CD34 - с 8 изопростаном, трансформирующим фактором роста B1, воздействием свинца.</p></abstract><trans-abstract xml:lang="en"><p>The features of biomechanisms of endometrial hyperplasia in subjects exposed to reproductive toxicants were inflammation and oxidative stress. An association of Ki67 expression with 8-hydroxydeoxyguanosine, length of service, CD34 expression with 8-isoprostane and both Ki67 and CD34 expression with transforming growth factor B1 and lead exposure established.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>репродуктивные токсиканты</kwd><kwd>гиперплазия эндометрия</kwd><kwd>воспаление</kwd><kwd>reproductive toxicants</kwd><kwd>endometrial hyperplasia</kwd><kwd>inflammation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
