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<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zurniimtpe</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина труда и промышленная экология</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Occupational Health and Industrial Ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1026-9428</issn><issn pub-type="epub">2618-8945</issn><publisher><publisher-name>FSBSI “Izmerov Research Institute of Occupational Health”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31089/1026-9428-2019-59-9-667-668</article-id><article-id custom-type="elpub" pub-id-type="custom">zurniimtpe-2275</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Вклад полиморфных вариантов некоторых генов-кандидатов в развитие артериальной гипертонии при воздействии винилхлорида</article-title><trans-title-group xml:lang="en"><trans-title>Certain candidate genes polymorphic variants impact in the development of hypertension when exposed to vinyl chloride</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кудаева</surname><given-names>Ирина Валерьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Kudaeva</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">Финансирование.Исследование не имело спонсорской поддержки</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дьякович</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dyakovich</surname><given-names>O. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ещина</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Eshchina</surname><given-names>I. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Восточно-Сибирский институт медико-экологических исследований»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>East-Siberian Institute of Medical and Ecological Research</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2019</year></pub-date><volume>0</volume><issue>9</issue><fpage>667</fpage><lpage>667</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кудаева И.В., Дьякович О.А., Ещина И.М., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Кудаева И.В., Дьякович О.А., Ещина И.М.</copyright-holder><copyright-holder xml:lang="en">Kudaeva I.V., Dyakovich O.A., Eshchina I.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.journal-irioh.ru/jour/article/view/2275">https://www.journal-irioh.ru/jour/article/view/2275</self-uri><abstract><p>У лиц, экспонированных винилхлоридом, риск развития артериальной гипертонией увеличивается в шесть раз у носителей генотипа С/С полиморфного варианта Leu28Pro гена APO E, в 9,5 раза - у носителей генотипа Т/Т полиморфного варианта C786T гена еNOS3 и в 1,75 раза - у носителей генотипа Т/С полиморфного варианта Met 235 Thr гена AGT.</p></abstract><trans-abstract xml:lang="en"><p>It was found that in persons exposed by vinyl chloride, the risk of hypertension increases six times in carriers of the genotype C/C polymorphic variant of Leu28Pro gene APO E, 9.5 times - in carriers of the genotype T/T polymorphic variant C786T gene eNOS3 and 1.75 times - in carriers of the genotype T/C polymorphic variant Met 235 Thr gene AGT.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>полиморфизм генов</kwd><kwd>артериальная гипертония</kwd><kwd>винилхлорид</kwd><kwd>gene polymorphism</kwd><kwd>arterial hypertension</kwd><kwd>vinyl chloride</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
