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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zurniimtpe</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина труда и промышленная экология</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Occupational Health and Industrial Ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1026-9428</issn><issn pub-type="epub">2618-8945</issn><publisher><publisher-name>FSBSI “Izmerov Research Institute of Occupational Health”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31089/1026-9428-2019-59-9-536-537</article-id><article-id custom-type="elpub" pub-id-type="custom">zurniimtpe-2167</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Иммунологические механизмы хронических поражений печени при воздействии химических веществ</article-title><trans-title-group xml:lang="en"><trans-title>Immunological mechanisms of chronic liver lesions under the influence of chemicals</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Агзамова</surname><given-names>Гулнара Суннатовна</given-names></name><name name-style="western" xml:lang="en"><surname>Agzamova</surname><given-names>G. S.</given-names></name></name-alternatives><email xlink:type="simple">Agzamova_gulya@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абдуллаева</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Abdullaeva</surname><given-names>M. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ташкентская медицинская академия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tashkent Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2019</year></pub-date><volume>0</volume><issue>9</issue><fpage>536</fpage><lpage>537</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Агзамова Г.С., Абдуллаева М.М., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Агзамова Г.С., Абдуллаева М.М.</copyright-holder><copyright-holder xml:lang="en">Agzamova G.S., Abdullaeva M.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.journal-irioh.ru/jour/article/view/2167">https://www.journal-irioh.ru/jour/article/view/2167</self-uri><abstract><p>Изучен иммунологический профиль хронических поражений печени в зависимости от токсического агента. Выявлено, что хроническое отравление производственными токсическими веществами вызывает изменения в функциональном состоянии Т-системы иммунитета, длительный контакт с производственными химическими веществами приводит к повышению сенсибилизации к аутоантигенам организма.</p></abstract><trans-abstract xml:lang="en"><p>The immunological profile of chronic liver lesions depending on the toxic agent was studied. It was revealed that chronic poisoning by industrial toxic substances causes changes in the functional state of the T-system of immunity, long-term contact with industrial chemicals leads to increased sensitization to autoantigens of the body.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническое поражение печени</kwd><kwd>иммунологические изменения</kwd><kwd>пестициды</kwd><kwd>свинец</kwd><kwd>органические растворители</kwd><kwd>chronic liver damage</kwd><kwd>immunological changes</kwd><kwd>pesticides</kwd><kwd>lead</kwd><kwd>organic solvents</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
