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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zurniimtpe</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина труда и промышленная экология</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Occupational Health and Industrial Ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1026-9428</issn><issn pub-type="epub">2618-8945</issn><publisher><publisher-name>FSBSI “Izmerov Research Institute of Occupational Health”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31089/1026-9428-2019-59-10-844-849</article-id><article-id custom-type="elpub" pub-id-type="custom">zurniimtpe-1422</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Обоснование модели управления профессиональным риском на производствах пенополиуретанов</article-title><trans-title-group xml:lang="en"><trans-title>Justifi cation of occupational risk management model in polyurethane foam production</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федотова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedotova</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Федотова Ирина Викторовна, зав. отделом гигиены</p><p>д-р мед. наук</p></bio><bio xml:lang="en"><p>Irina V. Fedotova, Head Department of Hygiene</p><p>Dr. of Sci. (Med.)</p></bio><email xlink:type="simple">irinavfed@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлова</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhaylova</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="en"><p>Svetlana A. Mikhaylova</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФБУН «Нижегородский научно-исследовательский институт гигиены и профпатологии» Роспотребнадзора</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Nizhny Novgorod Research Institute for Hygiene and Occupational Pathology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Приволжский исследовательский медицинский университет» Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Privolzhskiy Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>12</day><month>11</month><year>2019</year></pub-date><volume>1</volume><issue>10</issue><fpage>844</fpage><lpage>849</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Федотова И.В., Михайлова С.А., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Федотова И.В., Михайлова С.А.</copyright-holder><copyright-holder xml:lang="en">Fedotova I.V., Mikhaylova S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.journal-irioh.ru/jour/article/view/1422">https://www.journal-irioh.ru/jour/article/view/1422</self-uri><abstract><sec><title>Введение</title><p>Введение. Работники производств пенополиуретанов (ППУ) подвергаются воздействию различных вредных профессиональных факторов, которые обусловливают повышенный риск развития нарушений органов дыхания, нервной системы, онкологических заболеваний.</p><p>Цель исследования — на основании анализа условий труда и состояния здоровья работников современных производств ППУ обосновать систему управления профессиональным риском, направленную на его снижение.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Характеристика условий труда на 5-ти современных производствах ППУ дана на основе анализа большого объема лабораторно-инструментальных исследований профессиональных факторов. Состояние здоровья работников производства ППУ оценивалось по результатам периодического медицинского осмотра в динамике за ряд лет. Для оценки риска рассчитаны показатели отношения шансов, относительного риска, этиологической доли профессиональных факторов в стажевой группе 5 и более лет по отношению к стажевой группе 0–4 года для мужчин и женщин по нозологическим формам с оценкой различий по 95% доверительным интервалам и величине хи-квадрат (χ2 ).</p></sec><sec><title>Результаты</title><p>Результаты. Условия труда на производствах ППУ характеризуются воздействием комплекса химических веществ, из которых наиболее значимыми являются изоцианаты и амины. На работников влияют и такие факторы, как повышенный шум, тяжесть труда. Условия труда на производствах ППУ оцениваются как вредные первой — третьей степеней. Выявлен повышенный риск развития у работников болезней эндокринной, нервной, дыхательной систем и опорнодвигательного аппарата, уровень которого возрастает с увеличением стажа работы на производстве ППУ. Обоснованы требования к организации производственного процесса, мониторингу условий труда, совершенствованию медицинского обслуживания, направленные на профилактику нарушений состояния здоровья работников. Заключение. Современные производства ППУ характеризуются комплексом вредных профессиональных факторов, оказывающих неблагоприятное влияние на здоровье работников, что требует внедрения в практику унифицированной модели управления профессиональным риском, направленной на его снижение.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Employees of production of polyurethane foams (PUF) are exposed to various harmful occupational factors that cause an increased risk of respiratory disorders, nervous system, cancer.</p><p>The aim of the study was to substantiate the occupational risk management system aimed at its reduction on the basis of the analysis of working conditions and health of employees of modern production facilities of PUF.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The characteristics of working conditions at 5 modern PUF productions are given on the basis of the analysis of a large amount of laboratory and instrumental research of occupational factors; the state of workers’ health in the production of PUF was assessed by the results of periodic medical examination over a number of years. For risk assessment, indicators of odds ratio, relative risk, etiological fraction of occupational factors in a group of 5 years of work experience or more compared to a group of 0–4 years of work experience for men and women in nosological forms were calculated with an assessment of differences in 95% confidence intervals and the magnitude of chi-square (c2 ).</p></sec><sec><title>Results</title><p>Results. Working conditions in the production of PUF are characterized by exposure to a complex of chemicals, of which the most significant are isocyanates and amines. Workers are also affected by factors such as increased noise, the severity of work. Working conditions in the production of polyurethane foam are evaluated as harmful to the first to third degrees. The increased risk of development of diseases of endocrine, nervous, respiratory systems and musculoskeletal system in workers was revealed, the level of which increases with the increase of work experience in the production of PUF. The requirements to the organization of the production process, monitoring of working conditions, improvement of medical care aimed at the prevention of violations of the health status of employees are substantiated.</p></sec><sec><title>Conclusions</title><p>Conclusions. Modern production of PUF is characterized by a complex of harmful occupational factors that have an adverse impact on the health of employees, which requires the introduction of a unified model of occupational risk management aimed at reducing it.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>производства пенополиуретанов</kwd><kwd>условия труда</kwd><kwd>профессиональный риск</kwd></kwd-group><kwd-group xml:lang="en"><kwd>polyurethane foam production</kwd><kwd>working conditions</kwd><kwd>occupational risk</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гурвич В.Б., Кузьмин С.В., Ярушин С.В, Диконская О.В., Никонов Б.И., Малых О.Л. и др. Методические подходы к обеспечению санитарно-эпидемиологического благополучия на основе методологии управления риском для здоровья населения. 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