<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zurniimtpe</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина труда и промышленная экология</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Occupational Health and Industrial Ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1026-9428</issn><issn pub-type="epub">2618-8945</issn><publisher><publisher-name>FSBSI “Izmerov Research Institute of Occupational Health”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31089/1026-9428-2019-3-167-173</article-id><article-id custom-type="elpub" pub-id-type="custom">zurniimtpe-1326</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEW</subject></subj-group></article-categories><title-group><article-title>На пути к ликвидации профессионального рака в Российской Федерации: исследования, направленные на профилактику онкологических заболеваний (Часть 2)</article-title><trans-title-group xml:lang="en"><trans-title>Towards the elimination of occupational cancers in the Russian Federation: cancer research for cancer prevention</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шуц</surname><given-names>Дж.</given-names></name><name name-style="western" xml:lang="en"><surname>Schüz</surname><given-names>J.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Олссон</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Olsson</surname><given-names>A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Международное агентство по изучению рака Всемирной организации здравоохранения (МАИР), Секция окружающей среды и&#13;
радиации</institution><country>Франция</country></aff><aff xml:lang="en"><institution>International Agency for Research on Cancer (IARC), Section of Environment and Radiation</institution><country>France</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>31</day><month>03</month><year>2019</year></pub-date><volume>0</volume><issue>3</issue><fpage>167</fpage><lpage>173</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шуц Д., Олссон А., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Шуц Д., Олссон А.</copyright-holder><copyright-holder xml:lang="en">Schüz J., Olsson A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.journal-irioh.ru/jour/article/view/1326">https://www.journal-irioh.ru/jour/article/view/1326</self-uri><abstract><p>Количество злокачественных опухолей растет во всем мире, и Российская Федерация не является исключением: ожидаемое число новых случаев составит 587 622 в 2040 г. (529 062 в 2018 г.), что обусловливает актуальность профилактика злокачественных новообразований. Профессиональные злокачественные новообразования, связанные с воздействием канцерогенов на рабочем месте, относятся к числу предотвратимых, поскольку возможна минимизация риска их развития за счет применения соответствующих мер по защите работника. В Российской Федерации порядка 20 тыс. случаев злокачественных новообразований в год может быть связано с работой, однако из-за недостатка информации о различных профессиональных канцерогенах системный учет не ведется, поэтому истинная распространенность может быть выше. Российская Федерация выглядит особенно подходящей для изучения распространенности заболеваний профессиональными злокачественными новообразованиями, учитывая значительную численность работающего населения, развитую промышленность и хороший текущий надзор за рабочими местами. Полученные результаты могут быть информативны не только для ситуации в России, но и в глобальном масштабе. Национальная программы учета злокачественных новообразований должна включать: разработку правовой базы, регистрацию случаев профессиональных злокачественных опухолей, проведение крупномасштабных эпидемиологических исследований профессиональных злокачественных опухолей, разработку эффективных мер по защите работника от известных канцерогенов. Это приведет к созданию постоянно обновляемой системы контроля, направленной на ликвидацию профессиональных злокачественных новообразований в Российской Федерации.</p></abstract><trans-abstract xml:lang="en"><p>Cancer is increasing worldwide. Th e Russian Federation is no exception in this regard with an increase of the total number of new cases predicted to rise from 529,062 in 2018 to 587,622 in 2040. Th e present high burden and increase in incident cases at the same time increases the pressure on healthcare infrastructure and related costs. Th us, primary and secondary prevention of cancer becomes essential. Occupational cancers related to exposure at the workplace are among the preventable cancer burden, due to the modifi ability of the risk through minimisation of occupational exposures and adequate worker protection. For the Russian Federation, some 20,000 cancers each year may be att ributable to occupation, but systematic recording is currently lacking. As information is also lacking on the absolute eff ect of various occupational carcinogens in the Russian workforce due to lack of large-scale epidemiological studies and because for many suspected occupational carcinogens the evidence may become stronger, the true burden may in fact be higher. Th e Russian Federation appears particularly suitable for research into occupational cancer given the sizable workforce, the heavy industrialisation as well as the good documentation and workplace s urveillance over time, so that results are both informative for the situation in the Russian Federation and on a global scale. Five challenging but not unfeasible steps of nationwide population-based cancer registration, development of a legal framework for record linkage of registries and data collections, recording of occupational cancers, large scale epidemiological occupational cancer research and rigorous implementation of worker protection on known carcinogens, lead the way to a continuously updated cancer control plan that includes the elimination of occupational cancer in the Russian Federation.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак</kwd><kwd>профессия</kwd><kwd>производственные канцерогены</kwd><kwd>профилактика рака</kwd><kwd>Российская Федерация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cancer</kwd><kwd>occupation</kwd><kwd>workplace carcinogens</kwd><kwd>cancer prevention</kwd><kwd>Russian Federation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018; 0: 1–31.</mixed-citation><mixed-citation xml:lang="en">Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018; 0: 1–31.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Schüz J, Espina C, Wild CP. Primary prevention: a need for concerted action. Mol Oncol 2018; epub ahead of print Dec 24.</mixed-citation><mixed-citation xml:lang="en">Schüz J, Espina C, Wild CP. Primary prevention: a need for concerted action. Mol Oncol 2018; epub ahead of print Dec 24.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Stewart BW, Bray F, Forman D, Ohgaki H, Straif K, Ullrich A, Wild CP. Cancer prevention as part of precision medicine: plenty to be done. Carcinogenesis. 2016; 37:2–9.</mixed-citation><mixed-citation xml:lang="en">Stewart BW, Bray F, Forman D, Ohgaki H, Straif K, Ullrich A, Wild CP. Cancer prevention as part of precision medicine: plenty to be done. Carcinogenesis. 2016; 37:2–9.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Schüz J, Espina C, Villain P, Herrero R, Leon M.E., Minozzi S, et al. Working Groups of Scientiﬁc Experts. European Code against Cancer 4th Edition: 12 ways to reduce your cancer risk. Cancer Epidemiol 2015; 39 Suppl 1:S1–10.</mixed-citation><mixed-citation xml:lang="en">Schüz J, Espina C, Villain P, Herrero R, Leon M.E., Minozzi S, et al. Working Groups of Scientiﬁc Experts. European Code against Cancer 4th Edition: 12 ways to reduce your cancer risk. Cancer Epidemiol 2015; 39 Suppl 1:S1–10.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Forman D, Bray F, Brewster DH, Gombe Mbalawa C, Kohler B, Piñeros M, Steliarova-Foucher E, Swaminathan R, Ferlay J. Cancer Incidence in Five Continents, Vol. X (electronic version). Lyon: International Agency for Research on Cancer, 2013. Available from: http://ci5.iarc.fr, accessed [31/01/2019].</mixed-citation><mixed-citation xml:lang="en">Forman D, Bray F, Brewster DH, Gombe Mbalawa C, Kohler B, Piñeros M, Steliarova-Foucher E, Swaminathan R, Ferlay J. Cancer Incidence in Five Continents, Vol. X (electronic version). Lyon: International Agency for Research on Cancer, 2013. Available from: http://ci5.iarc.fr, accessed [31/01/2019].</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Villain P, Gonzalez P, Almonte M, Franceschi S, Dillner J, Anttila A. et al. European Code against Cancer 4th Edition: Infections and Cancer. Cancer Epidemiol 2015; 39 Suppl 1:S120–38.</mixed-citation><mixed-citation xml:lang="en">Villain P, Gonzalez P, Almonte M, Franceschi S, Dillner J, Anttila A. et al. European Code against Cancer 4th Edition: Infections and Cancer. Cancer Epidemiol 2015; 39 Suppl 1:S120–38.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Togawa K, Ahn H.S., Auvinen A, Bauer AJ, Brito J.P., Davies L. et al. Long-term strategies for thyroid health monitoring aﬅer nuclear accidents: recommendations from an Expert Group convened by IARC. Lancet Oncol. 2018; 19: 1280–3.</mixed-citation><mixed-citation xml:lang="en">Togawa K, Ahn H.S., Auvinen A, Bauer AJ, Brito J.P., Davies L. et al. Long-term strategies for thyroid health monitoring aﬅer nuclear accidents: recommendations from an Expert Group convened by IARC. Lancet Oncol. 2018; 19: 1280–3.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Espina C, Straif K, Friis S, Kogevinas M, Saracci R, Vainio H, Schüz J. European Code against Cancer 4th Edition: Environment, occupation and cancer. Cancer Epidemiol. 2015; 39 Suppl 1: S84–92.</mixed-citation><mixed-citation xml:lang="en">Espina C, Straif K, Friis S, Kogevinas M, Saracci R, Vainio H, Schüz J. European Code against Cancer 4th Edition: Environment, occupation and cancer. Cancer Epidemiol. 2015; 39 Suppl 1: S84–92.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Espina C, Porta M, Schüz J, Aguado I.H., Percival R.V., Dora C. et al. Environmental and occupational interventions for primary prevention of cancer: a cross-sectorial policy framework. Environ Health Perspect 2013; 121:420–6.</mixed-citation><mixed-citation xml:lang="en">Espina C, Porta M, Schüz J, Aguado I.H., Percival R.V., Dora C. et al. Environmental and occupational interventions for primary prevention of cancer: a cross-sectorial policy framework. Environ Health Perspect 2013; 121:420–6.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Marant Micallef C, Shield K.D., Vignat J., Baldi I., Charbotel B., Fervers B. et al. Cancers in France in 2015 attributable to occupational exposures. Int J Hyg Environ Health. 2019; 222: 22–9.</mixed-citation><mixed-citation xml:lang="en">Marant Micallef C, Shield K.D., Vignat J., Baldi I., Charbotel B., Fervers B. et al. Cancers in France in 2015 attributable to occupational exposures. Int J Hyg Environ Health. 2019; 222: 22–9.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Brown KF, Rumgay H, Dunlop C, Ryan M, Quartly F, Cox A, Deas A, Elliss-Brookes L, Gavin A, Hounsome L, Huws D, Ormiston-Smith N, Shelton J, White C, Parkin DM. The fraction of cancer attributable to modiﬁable risk factors in England, Wales, Scotland, Northern Ireland, and the United Kingdom in 2015. Br J Cancer. 2018; 118: 1130–41.</mixed-citation><mixed-citation xml:lang="en">Brown KF, Rumgay H, Dunlop C, Ryan M, Quartly F, Cox A, Deas A, Elliss-Brookes L, Gavin A, Hounsome L, Huws D, Ormiston-Smith N, Shelton J, White C, Parkin DM. The fraction of cancer attributable to modiﬁable risk factors in England, Wales, Scotland, Northern Ireland, and the United Kingdom in 2015. Br J Cancer. 2018; 118: 1130–41.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Doll R, Peto R. The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today. J Natl Cancer Inst. 1981; 66: 1191–308.</mixed-citation><mixed-citation xml:lang="en">Doll R, Peto R. The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today. J Natl Cancer Inst. 1981; 66: 1191–308.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Schonfeld SJ, McCormack V, Rutherford MJ, Schüz J. Regional variations in German mesothelioma mortality rates: 2000– 2010. Cancer Causes Control 2014; 25:615–24.</mixed-citation><mixed-citation xml:lang="en">Schonfeld SJ, McCormack V, Rutherford MJ, Schüz J. Regional variations in German mesothelioma mortality rates: 2000– 2010. Cancer Causes Control 2014; 25:615–24.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Cogliano VJ, Baan R, Straif K, Grosse Y, Lauby-Secretan B, El Ghissassi F, Bouvard V, Benbrahim-Tallaa L, Guha N, Freeman C, Galichet L, Wild CP. Preventable exposures associated with human cancers. J Natl Cancer Inst. 2011; 103: 1827–39.</mixed-citation><mixed-citation xml:lang="en">Cogliano VJ, Baan R, Straif K, Grosse Y, Lauby-Secretan B, El Ghissassi F, Bouvard V, Benbrahim-Tallaa L, Guha N, Freeman C, Galichet L, Wild CP. Preventable exposures associated with human cancers. J Natl Cancer Inst. 2011; 103: 1827–39.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Rushton L, Bagga S, Bevan R, Brown TP, Cherrie JW, Holmes P et al. Occupation and cancer in Britain. Br J Cancer. 2010; 102: 1428–37.</mixed-citation><mixed-citation xml:lang="en">Rushton L, Bagga S, Bevan R, Brown TP, Cherrie JW, Holmes P et al. Occupation and cancer in Britain. Br J Cancer. 2010; 102: 1428–37.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Forman D, Bauld L, Bonanni B, Brenner H, Brown K, Dillner J. et al. Time for a European initiative for research to prevent cancer: A manifesto for Cancer Prevention Europe (CPE). J Cancer Policy. 2018; 17: 15–23.</mixed-citation><mixed-citation xml:lang="en">Forman D, Bauld L, Bonanni B, Brenner H, Brown K, Dillner J. et al. Time for a European initiative for research to prevent cancer: A manifesto for Cancer Prevention Europe (CPE). J Cancer Policy. 2018; 17: 15–23.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Leuraud K, Richardson DB, Cardis E, Daniels RD, Gillies M, O’Hagan J. et al. Ionising radiation and risk of death from leukaemia and lymphoma in radiation-monitored workers (INWORKS): an international cohort study. Lancet Haematol. 2015; 2: e276–81</mixed-citation><mixed-citation xml:lang="en">Leuraud K, Richardson DB, Cardis E, Daniels RD, Gillies M, O’Hagan J. et al. Ionising radiation and risk of death from leukaemia and lymphoma in radiation-monitored workers (INWORKS): an international cohort study. Lancet Haematol. 2015; 2: e276–81</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Richardson DB, Cardis E, Daniels RD, Gillies M, O’Hagan J, Hamra G.B. et al. Risk of cancer from occupational exposure to ionizing radiation: retrospective cohort study of workers in France, the United Kingdom, and the United States (INWORKS). BMJ. 2015; 351: h5359.</mixed-citation><mixed-citation xml:lang="en">Richardson DB, Cardis E, Daniels RD, Gillies M, O’Hagan J, Hamra G.B. et al. Risk of cancer from occupational exposure to ionizing radiation: retrospective cohort study of workers in France, the United Kingdom, and the United States (INWORKS). BMJ. 2015; 351: h5359.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Schonfeld SJ, Winde F, Albrecht C, Kielkowski D, Liefferink M, Patel M, Sewram V, Stoch L, Whitaker C, Schüz J; the workshop participants. Health effects in populations living around the uraniferous gold mine tailings in South Africa: Gaps and opportunities for research. Cancer Epidemiol. 2014; 38: 628–32.</mixed-citation><mixed-citation xml:lang="en">Schonfeld SJ, Winde F, Albrecht C, Kielkowski D, Liefferink M, Patel M, Sewram V, Stoch L, Whitaker C, Schüz J; the workshop participants. Health effects in populations living around the uraniferous gold mine tailings in South Africa: Gaps and opportunities for research. Cancer Epidemiol. 2014; 38: 628–32.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Olsson AC, Xu Y, Schüz J, Vlaanderen J, Kr omhout H, Vermeulen R. et al. Lung cancer risk among hairdressers: a pooled analysis of case-control studies conducted between 1985 and 2010. Am J Epidemiol. 2013; 178:1355–65.</mixed-citation><mixed-citation xml:lang="en">Olsson AC, Xu Y, Schüz J, Vlaanderen J, Kr omhout H, Vermeulen R. et al. Lung cancer risk among hairdressers: a pooled analysis of case-control studies conducted between 1985 and 2010. Am J Epidemiol. 2013; 178:1355–65.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Pukkala E, Martinsen JI, Lynge E, Gunnarsdottir HK, Sparén P, Tryggvadottir L, Weiderpass E, Kjaerheim K. Occupation and cancer — follow-up of 15 million people in ﬁve Nordic countries. Acta Oncol. 2009; 48:646–790.</mixed-citation><mixed-citation xml:lang="en">Pukkala E, Martinsen JI, Lynge E, Gunnarsdottir HK, Sparén P, Tryggvadottir L, Weiderpass E, Kjaerheim K. Occupation and cancer — follow-up of 15 million people in ﬁve Nordic countries. Acta Oncol. 2009; 48:646–790.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Schüz J, Schonfeld SJ, Kromhout H, Straif K, Kashanskiy SV, Kovalevskiy EV, Bukhtiyarov IV, McCormack V. A retrospective cohort study of cancer mortality in employees of a Russian chrysotile asbestos mine and mills: study rationale and key features. Cancer Epidemiol. 2013; 37: 440–5.</mixed-citation><mixed-citation xml:lang="en">Schüz J, Schonfeld SJ, Kromhout H, Straif K, Kashanskiy SV, Kovalevskiy EV, Bukhtiyarov IV, McCormack V. A retrospective cohort study of cancer mortality in employees of a Russian chrysotile asbestos mine and mills: study rationale and key features. Cancer Epidemiol. 2013; 37: 440–5.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
